DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001101779.1	Gene:	Sec14l1 / 360668	RGDID:	1563123	Length:	720	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	55/310 - (17%)
Similarity:	114/310 - (36%)	Gaps:	72/310 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSG---SSPNSIRPLPPGLQKVAIEE------LNEVPSRVESDIAALKEWLQKQPHLCACLEDQF 56
            :||   |||.::.....|.....::.      |.::....||.:..|::||| :.|.....:|:.
  Rat   217 LSGEVLSSPGTVAEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQ-ETHKGKIPKDEH 280

  Fly    57 LLSFLRGSKFSLEKAKQ------------KIDRFYSLQAVIPEVFNDQRLVDNAQVLEIIRLGVI 109
            :|.|||...|:::||::            ::|  |.|....|           .|||:....|..
  Rat   281 ILRFLRARDFNIDKAREIMCQSLTWRKQHQVD--YILDTWTP-----------PQVLQDYYAGGW 332

  Fly   110 LRIPLDEEDTGPAVTIIRAGSYDINKFKFQDIIRVGSMFGEIMMLE-------------DDNASV 161
            ..    .:..|..:.::|.|..|.     :.::|.   .||..:|.             ::|..|
  Rat   333 HH----HDKDGRPLYVLRLGQMDT-----KGLVRA---LGEEALLRYVLSINEEGLRRCEENTKV 385

  Fly   162 -----SGYLEIMDMSGVTGANLFALQPQLLSKFSAYADEAMPTRQKGIHFINVPKAFETGFKSLL 221
                 |.:..::|:.|:...:|:....:.|.:.....:...|.....:..:..|:.|...:..:.
  Rat   386 FGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVS 450

  Fly   222 GWFPGKIKER--VSVSSD---PEAIFERVPKHYLPEEYGGSKGTMKDITD 266
            .:.....:.:  :...:|   |..:.:.:.|..:|:...|.  .|.|:.:
  Rat   451 PFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGE--CMCDVPE 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	15/56 (27%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	24/177 (14%)
Sec14l1	NP_001101779.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	257..302	CDD:215024	15/45 (33%)
		CRAL_TRIO	327..491	CDD:279044	23/175 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810