DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	62/322 - (19%)
Similarity:	118/322 - (36%)	Gaps:	91/322 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ESDIAALKEWLQKQPHLCACLEDQFLLSFLRGSKFSLEKAKQKIDRFYSLQAVIPEVFNDQRLVD 96
            ||.:..|:.||| :.|.....:|:.:|.|||...|.|:||:..:.:..|        :..|..||
  Rat   243 ESCLVQLRRWLQ-ETHKGKIPKDEHILRFLRARDFHLDKARDMLCQSLS--------WRKQHQVD 298

  Fly    97 NAQVLEIIRLGVILR-----IPLDEEDTGPAVTIIRAGSYDINKFKFQD-------IIRVGSM-- 147
                       ::|:     .||.|         ..||.:     .:||       |:|:|.|
  Rat   299 -----------LLLQTWRPPAPLQE---------FYAGGW-----HYQDIDGRPLYILRLGQMDT 338

  Fly   148 ------FGEIMMLE-------------DDNA-----SVSGYLEIMDMSGVTGANLFALQPQLLSK 188
                  .||..:|:             :.|.     .:|.:..::|:.|:...:|:....:.|.:
  Rat   339 KGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLR 403

  Fly   189 FSAYADEAMPTRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSVSS-----DPEAIFERVPKH 248
            .....::..|.....:..:..|:.|...:..:..:.....:.:..:.|     .|..:.:.:.|.
  Rat   404 MIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKD 468

  Fly   249 YLPEEYGGSKGTMKDITDQMEAKLCSYRSYFEDCQHFGAHDKLRE------EASVL--NPDE 302
            .:|:..||     :.:.:..|..:.....|..:.:...| |:||:      .||||  :|.|
  Rat   469 VIPDFLGG-----ESVCNVPEGGMVPKSLYLTEEEQEQA-DQLRQWSETYHSASVLRGSPHE 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	16/44 (36%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	28/197 (14%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	21/85 (25%)
		CRAL_TRIO_N	243..288	CDD:215024	16/45 (36%)
		CRAL_TRIO	314..477	CDD:306996	26/172 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900