Protein Alignment CG33965 and CLVS1

DIOPT Version :10

• Sequence 1: NP_001033983.1
• Gene: CG33965 / 3885668
• FlyBaseID: FBgn0053965
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_775790.1
• Gene: CLVS1 / 157807
• HGNCID: 23139
• Length: 354
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 66/286 - (23%)
• Similarity: 132/286 - (46%)
• Gaps: 26/286 - (9%)

  Fly    12 LPPGLQKVAIE----ELNEVPSRVESDIAALKEWLQKQPHL-CACLEDQFLLSFLRGSKFSLEKA 71
            |..||....||    ||||.|..:..||..:::.:..:|.: ....:|.|:|.|||..||....|
Human    26 LQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADA 90

  Fly    72 KQKIDRFYSLQAVIPEVFNDQRLVDNAQVLEIIRLGVILRIP--LDEED-TGPAVTIIRAGSYDI 133
            .:.:.:::..:.:..::|.:.:..|..     |:..:|...|  |:..| .|..:.::.|.::|.
Human    91 FRLLAQYFQYRQLNLDMFKNFKADDPG-----IKRALIDGFPGVLENRDHYGRKILLLFAANWDQ 150

  Fly   134 NKFKFQDIIRVGSMFGEIMMLEDDNASVSGYLEIMDMSGVTGANLFALQPQLLSKFSAYADEAMP 198
            ::..|.||:|...:..|: ::||....::|::.|:|.|..:......|.|.:|........::.|
Human   151 SRNSFTDILRAILLSLEV-LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFP 214

  Fly   199 TRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSV-SSDPEAIFERVPKHYLPEEYGGS----- 257
            .|..|:||:|.|......:..:..:...|.::|:.: .::..::.:.:...:||.|:||:
Human   215 ARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYD 279

  Fly   258 KGTM------KDITDQMEAKLCSYRS 277
            .||.      .|.:|:.:....||.:
Human   280 MGTWARTLLGPDYSDENDYTHTSYNA 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	12/45 (27%)
		CRAL_TRIO	120..256	CDD:459890	29/136 (21%)
CLVS1	NP_775790.1	CRAL_TRIO_N	51..97	CDD:215024	12/45 (27%)
		SEC14	123..274	CDD:469559	34/151 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..354