DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	271	Identity:	55/271 - (20%)
Similarity:	106/271 - (39%)	Gaps:	57/271 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ELNEVPSRVESDIAALKEWLQKQPHLCACLEDQFLLSFLRGSKFSLEKAKQKIDRFYSLQAVIPE 87
            ::.::..:.:..:|..:|.||.........:|.|||.:||...|.|:|::..:.:...
Mouse     4 QVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVE------- 61

  Fly    88 VFNDQRLVDNA---QVLEIIRLGVILRIPLDEEDTGPAVTIIRAGSYDIN--------------K 135
             |.:|:.:|..   |..|:|:|          .|:|      ....||..              |
Mouse    62 -FRNQQNLDQILTWQAPEVIQL----------YDSG------GLSGYDYEGCPVWFDIIGTMDPK 109

  Fly   136 FKF-----QDIIRVGSMFGEIMMLEDDNAS------VSGYLEIMDMSGVTGANLFALQPQLLSKF 189
            ..|     ||:||......|:::.|.:..|      :...:.:.||.|::..:|:....::..:|
Mouse   110 GLFMSASKQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQF 174

  Fly   190 SAYADEAMPTRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSV--SSDPEAIFERVPKHYLPE 252
            .|..:...|...|.:..|..||.|...|..:..:...:.::::.:  .:..:.:.:.|....||.
Mouse   175 FAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPV 239

  Fly   253 EYGGSKGTMKD 263
            |:|   |||.|
Mouse   240 EFG---GTMTD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	13/44 (30%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	33/181 (18%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	13/45 (29%)
		SEC14	77..244	CDD:214706	34/185 (18%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810