DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and BARX1

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_067545.3	Gene:	BARX1 / 56033	HGNCID:	955	Length:	254	Species:	Homo sapiens

Alignment Length:	236	Identity:	62/236 - (26%)
Similarity:	89/236 - (37%)	Gaps:	73/236 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PHLEQDKSRLNSCIEKSIQTKKKGKLGA--------------FSIDSILSTSEAHSSQNSLPKDN 53
            ||      |..|.:.:.|.|:..|..||              |.:.::|:....||        :
Human    23 PH------RYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHS--------H 73

  Fly    54 TNVTSSDISKLYAFSFTQEGNNKTPLTNFDLCQGHPRRLPITFDGSTVSRFVWRTESILPSYITN 118
            ..|..::.:.::.|.....|           |.|....|.....|             ||. ...
Human    74 LAVLKAEQAAVFKFPLAPLG-----------CSGLSSALLAAGPG-------------LPG-AAG 113

  Fly   119 STNLQ-EKQLR-------------KRFTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKS 169
            :.:|. |.|||             |....|:.|..::..||..||..|...||||...|::|::|
Human   114 APHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAES 178

  Fly   170 LSLTEVQVKTWFQNRRTKWKKQLTSRLKIAHRHGLWIPTLP 210
            |.|:::|||||:||||.||||      .:....||..||.|
Human   179 LGLSQLQVKTWYQNRRMKWKK------IVLQGGGLESPTKP 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	25/52 (48%)
BARX1	NP_067545.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Homeobox	145..199	CDD:395001	26/53 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..254		5/10 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810