DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and lum

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001011006.1	Gene:	lum / 496415	XenbaseID:	XB-GENE-1004934	Length:	353	Species:	Xenopus tropicalis

Alignment Length:	184	Identity:	36/184 - (19%)
Similarity:	64/184 - (34%)	Gaps:	55/184 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IQTKKKGKLGAFSIDSILSTSEAHSSQNSLPKDNTNVTSSDISKL--YAFSFTQEGNNKTPLTNF 82
            :...|..|:....::.:.:.:..|...|:|.:|:.:.....:.:|  ...||    |..|.|
Frog   157 VTNNKISKITPNILEGLENLTHIHLQYNALKEDSISGAFKGLKQLEYLDLSF----NELTKL--- 214

  Fly    83 DLCQGHPRRLP-----ITFDGSTVSRFVWRTESILPSYITNSTNLQEKQL--RKRFTDRKPRQAY 140
                  |:.||     :.||.:.::       :|...:......||..:|  .|......|..|:
Frog   215 ------PKGLPPSITTLYFDNNKIA-------NIPDEFFQGFKALQYLRLSNNKLKDGGVPGNAF 266

  Fly   141 SASQL-----------------ERLEN---------EFNLDKYLSVSKRVELSK 168
            :.|.|                 |.|||         :|||:.:..:...:|.||
Frog   267 NISSLVELDLSFNELGSIPAVNEGLENLYLQVNKIQKFNLNSFCKIIGPLEYSK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	14/59 (24%)
lum	NP_001011006.1	PRK15370	<56..>256	CDD:185268	21/118 (18%)
		leucine-rich repeat	81..104	CDD:275380
		leucine-rich repeat	105..130	CDD:275380
		leucine-rich repeat	131..151	CDD:275380
		leucine-rich repeat	152..175	CDD:275380	2/17 (12%)
		leucine-rich repeat	176..200	CDD:275380	4/23 (17%)
		leucine-rich repeat	201..221	CDD:275380	9/32 (28%)
		leucine-rich repeat	222..245	CDD:275380	3/29 (10%)
		PLN03150	<235..>307	CDD:178695	15/71 (21%)
		leucine-rich repeat	246..270	CDD:275380	6/23 (26%)
		leucine-rich repeat	271..294	CDD:275380	4/22 (18%)
		leucine-rich repeat	295..320	CDD:275380	4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000