DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34031 and zfh2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_524623.2	Gene:	zfh2 / 43795	FlyBaseID:	FBgn0004607	Length:	3005	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	53/205 - (25%)
Similarity:	86/205 - (41%)	Gaps:	42/205 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NPHLEQDKSRL-NSCIEKSIQTKKKGKLGAFSIDSILSTSEAHS---SQNSLPKDNTNVTSSDIS 62
            |....||:|.| .|.:..:.|:::  ::..|...|...:|:..|   |.||....|...:.:|:
  Fly  2033 NADTAQDQSLLAGSSLASNCQSQQ--QINIFETKSESGSSDVLSRPPSPNSGAAGNVYGSMNDL- 2094

  Fly    63 KLYAFSFTQEGNNKTPLTNFDLCQGHPRRLPI---TFD---------GSTVSRFVWRTESILPSY 115
                  ..|:      |.|.....|.|:::.|   ||:         ||..::|  .:.|...|.
  Fly  2095 ------LNQQ------LENMGSNMGPPKKMQIVGKTFEKNVAPMVTSGSVSTQF--ESNSSNSSS 2145

  Fly   116 ITNSTNLQEKQLRKRFTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTW 180
            .::||:..::..|.||||         .|::.|:..|..:.|...|....|||.|.|:...:..|
  Fly  2146 SSSSTSGGKRANRTRFTD---------YQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVW 2201

  Fly   181 FQNRRTKWKK 190
            |||.|.|.:|
  Fly  2202 FQNARQKQRK 2211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	16/52 (31%)
zfh2	NP_524623.2	C2H2 Zn finger	561..581	CDD:275368
		C2H2 Zn finger	616..633	CDD:275368
		C2H2 Zn finger	1515..1542	CDD:275371
		C2H2 Zn finger	1543..1564	CDD:275371
		HOX	1797..1853	CDD:197696
		Homeobox	2158..2210	CDD:278475	21/60 (35%)
		Homeobox	2764..2816	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910