DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and BARHL2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_064447.1	Gene:	BARHL2 / 343472	HGNCID:	954	Length:	387	Species:	Homo sapiens

Alignment Length:	191	Identity:	61/191 - (31%)
Similarity:	88/191 - (46%)	Gaps:	46/191 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AFSIDSILSTSE----------AHSSQNSLPKDNTN-VTSSDISKLYAFSFTQEGNNKTPL---- 79
            :|.|..||..|:          :.||.:..||..:| |..|...||      ::.::||.|
Human   141 SFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKL------EQEDSKTKLDKRE 199

  Fly    80 -TNFDL-CQGHPRRLPITFDGSTVSRFVWRTESILPSYITNSTNLQEKQLRKRFTDRKPRQAYSA 142
             :..|: |.|                    |:......||:|......:.:|   .||.|.|:|.
Human   200 DSQSDIKCHG--------------------TKEEGDREITSSRESPPVRAKK---PRKARTAFSD 241

  Fly   143 SQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQLTSRLKIAHRHG 203
            .||.:||..|...|||||..|::|:.:|:||:.|||||:||||||||:|....|::....|
Human   242 HQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAG 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	29/52 (56%)
BARHL2	NP_064447.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..145		1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..240		24/111 (22%)
		Homeobox	236..288	CDD:278475	29/51 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	367..387
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810