DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and HOXD4

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_055436.2	Gene:	HOXD4 / 3233	HGNCID:	5138	Length:	255	Species:	Homo sapiens

Alignment Length:	142	Identity:	40/142 - (28%)
Similarity:	65/142 - (45%)	Gaps:	45/142 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 QGHPRRLPITFDGSTVSR----FVW----RTESILPSYITNSTNLQEKQLRKRFTDRKPRQAYSA 142
            |..|::.|   .|:.:.:    :.|    ...|:.|:|....             .::.|.||:.
Human   115 QSDPKQPP---SGTALKQPAVVYPWMKKVHVNSVNPNYTGGE-------------PKRSRTAYTR 163

  Fly   143 SQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQLTSRLKIAHRHGLWIP 207
            .|:..||.||:.::||:..:|:|::.:|.|:|.|:|.||||||.||||.        |:
Human   164 QQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKD--------HK------ 214

  Fly   208 TLPITTIIPNTK 219
                   :||||
Human   215 -------LPNTK 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	24/52 (46%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..127		4/14 (29%)
		Antp-type hexapeptide	133..138		1/4 (25%)
		Homeobox	157..210	CDD:306543	24/52 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..255		5/29 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910