DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34031 and nkx2.2a

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001295569.1	Gene:	nkx2.2a / 30697	ZFINID:	ZDB-GENE-980526-403	Length:	273	Species:	Danio rerio

Alignment Length:	206	Identity:	55/206 - (26%)
Similarity:	86/206 - (41%)	Gaps:	38/206 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SIQTKKKGKLGAFSIDSILSTSEAHSSQNSLPKDNTNVTSSDISKLYAFSFTQEGNNKTPLTNFD 83
            |:...|.|    ||:..||...:.:..:.|:.....:...|:.:|      |.....::||.|
Zfish     6 SLTNTKTG----FSVKDILDLPDTNDEEGSITGTEEDTEGSEATK------TPGVLVQSPLEN-- 58

  Fly    84 LCQGHPRRLPITFDGS--TVSRFVWRTESILPSYITNSTNLQ-----------------EKQLRK 129
             .|..|.:.|. :|.|  ..:|::..|:||..|....|.|.|                 :|:...
Zfish    59 -VQNLPLKNPF-YDNSDNPYTRWLATTDSIQYSLHGLSANSQDTSAKSPEPSADESPDNDKETSS 121

  Fly   130 RFTD----RKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKK 190
            ..:|    ||.|..:|.:|...||..|...:|||..:|..|:..:.||..|||.||||.|.|.|:
Zfish   122 NGSDSGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 186

  Fly   191 QLTSR-LKIAH 200
            ....: :::.|
Zfish   187 ARAEKGMEVTH 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	22/52 (42%)
nkx2.2a	NP_001295569.1	COG5576	93..218	CDD:227863	31/105 (30%)
nkx2.2a	NP_001295569.1	Homeobox	132..185	CDD:278475	22/52 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910