DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and rx1

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_571300.2	Gene:	rx1 / 30472	ZFINID:	ZDB-GENE-990415-236	Length:	330	Species:	Danio rerio

Alignment Length:	209	Identity:	56/209 - (26%)
Similarity:	85/209 - (40%)	Gaps:	36/209 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 HLEQDKSRL--NSCIEKS---IQTKKKGKL---GAFSIDSILSTSEAHSSQNSLPKDNTNVTSSD 60
            ||..|...:  :||:..|   ...|..|.:   ...|||.||..::   .|:||.....|..:
Zfish     2 HLSLDTMNMVDDSCLSPSNFHDMVKAGGAVVGTRVHSIDVILGFNK---DQDSLLNPGANAVA-- 61

  Fly    61 ISKLYAFSFTQEGNNKTPLTNFDLCQGHPRRLPITFDGSTVSRF-------------VWRTESIL 112
             .|:...|..:.|.....:..:    ||   ||...|||....|             :......:
Zfish    62 -HKVGGESLGEPGKLDQRVQPY----GH---LPPLRDGSEQPTFHDADMFSNKCDGDLGDLRKAI 118

  Fly   113 PSYITNSTNLQEKQLRKRFTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQV 177
            .|...:..:...:|.:|:  .|:.|..::..||..||..|....|..|..|.||:..::|.||:|
Zfish   119 ESDSKSPDSADGEQPKKK--HRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRV 181

  Fly   178 KTWFQNRRTKWKKQ 191
            :.||||||.||::|
Zfish   182 QVWFQNRRAKWRRQ 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	22/52 (42%)
rx1	NP_571300.2	Octapeptide motif	37..44		4/6 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..104		10/44 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..142		4/25 (16%)
		Homeobox	141..193	CDD:278475	22/51 (43%)
		OAR	302..318	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
		Nuclear localization signal. /evidence=ECO:0000255	312..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910