DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and GBX2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001476.2	Gene:	GBX2 / 2637	HGNCID:	4186	Length:	348	Species:	Homo sapiens

Alignment Length:	169	Identity:	51/169 - (30%)
Similarity:	77/169 - (45%)	Gaps:	37/169 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SILSTSEAHSSQNSL-------PKDNTNVTSSDISKLYAFS------FTQEGNNKTPLTNFDLCQ 86
            |:|:.|.|.:.|.||       .||.:.|......|..:||      ::.:.|......:.:...
Human   160 SLLAFSAAETVQASLVGAVRGQGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDP 224

  Fly    87 GHPRRLPITFDGSTVSRFVWRTESILPSYITNSTNLQEKQLRKRFTDRKPRQAYSASQLERLENE 151
            ||.........|:..|              |.||.          .:|:.|.|:::.||..||.|
Human   225 GHALEETPPSSGAAGS--------------TTSTG----------KNRRRRTAFTSEQLLELEKE 265

  Fly   152 FNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKK 190
            |:..||||:::|.:::.:|.|:|||||.||||||.|||:
Human   266 FHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	27/52 (52%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..81
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	111..139
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..251		15/95 (16%)
		Homeobox	250..303	CDD:306543	27/52 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910