DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and Shox2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_038693.1	Gene:	Shox2 / 20429	MGIID:	1201673	Length:	331	Species:	Mus musculus

Alignment Length:	121	Identity:	35/121 - (28%)
Similarity:	54/121 - (44%)	Gaps:	12/121 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GNNKTPLTNFDLCQGHPRRLPITFDGSTVSRFVWRTESILPSYITNSTNLQ--EKQLRKRFTDRK 135
            |..::|:...|:......|.|    ||.      |...:.|.......:.:  |.:.:.:...|:
Mouse    88 GGGRSPVRELDMGAAERSREP----GSP------RLTEVSPELKDRKDDAKGMEDEGQTKIKQRR 142

  Fly   136 PRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQ 191
            .|..::..||..||..|:...|.....|.|||:.|.|:|.:|:.||||||.|.:||
Mouse   143 SRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	22/52 (42%)
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..140		10/61 (16%)
		Homeobox	143..197	CDD:395001	22/53 (42%)
		OAR	311..327	CDD:397759
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	313..326
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910