DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and Nkx1-2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_033149.1	Gene:	Nkx1-2 / 20231	MGIID:	104806	Length:	305	Species:	Mus musculus

Alignment Length:	118	Identity:	51/118 - (43%)
Similarity:	68/118 - (57%)	Gaps:	9/118 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 DLCQGH-PRRLPITFDGSTVSRFV-WRTESI----LPSYITNSTNLQEKQLRKRFTDRKPRQAYS 141
            |..:.| |.|.....:||..:|.| ..||..    ||:...:..:.:.::.|...:..|||:|.:
Mouse    97 DAGRAHQPERWQGVHEGSPEARAVAVGTEESGAEGLPASPGSPGSPRPRRRRAESSCAKPRRART 161

  Fly   142 A---SQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQ 191
            |   .||..|||:|...:||||.:|:.|:.||||||.|||.||||||||||||
Mouse   162 AFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	33/55 (60%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..158		15/60 (25%)
		Homeobox	160..212	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..257		5/5 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900