DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34031 and Rax

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_038861.2	Gene:	Rax / 19434	MGIID:	109632	Length:	342	Species:	Mus musculus

Alignment Length:	199	Identity:	58/199 - (29%)
Similarity:	87/199 - (43%)	Gaps:	37/199 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SRLNSCIEKSIQ-TKKKGKLGAFSIDSILSTSEAH----SSQNSLPKDNTNVTSSDISKLYAFSF 69
            |||:| ||..:. ||:.|.|..|..:....:|:..    .:|.:.||  .....|:.|...|..|
Mouse    30 SRLHS-IEAILGFTKEDGILDTFPAERSSRSSKERDPRLGAQPACPK--APAGGSESSPPAAPGF 91

  Fly    70 TQEGNNKTPLTNFDLC----QGHPRRLPITFDGSTVSRFVWRTESILPSYITNSTNLQEKQLRKR 130
            ..|.....|      |    ||..|..|    |.:|.          |:  ...:.|.|::..|:
Mouse    92 VPEYEATRP------CYPKEQGEARPSP----GLSVG----------PA--AGDSKLSEEEPPKK 134

  Fly   131 FTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQLTSR 195
             ..|:.|..::..||..||..|....|..|..|.||:..::|.||:|:.||||||.||::|  .:
Mouse   135 -KHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQ--EK 196

  Fly   196 LKIA 199
            |:::
Mouse   197 LEVS 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	22/52 (42%)
Rax	NP_038861.2	Octapeptide motif	33..40		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..140		25/120 (21%)
		Homeobox	140..192	CDD:278475	22/51 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..295
		OAR	316..331	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910