DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and Pitx3

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	XP_006526827.1	Gene:	Pitx3 / 18742	MGIID:	1100498	Length:	388	Species:	Mus musculus

Alignment Length:	196	Identity:	50/196 - (25%)
Similarity:	86/196 - (43%)	Gaps:	24/196 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LGAFSIDSILSTSEAHSSQNSLPKDNTNVTSSDISK----LYAFSFTQEGNNKTP-LTNFDLCQG 87
            |||.|::|....|..:    .||...:.....:|.:    ...|....|...::| |:..|....
Mouse    50 LGAHSLNSACHCSGCY----PLPGPPSTEIEDEIKRQRPPSMEFGLLGEAEARSPALSLSDAGTP 110

  Fly    88 HPRRLPITFDGSTVSRF--VWRTESILPSYITNSTNLQEKQLRKRFTDRKPRQAYSASQLERLEN 150
            ||   |:...|......  ..:..:.||.......:|::||       |:.|..:::.||:.||.
Mouse   111 HP---PLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ-------RRQRTHFTSQQLQELEA 165

  Fly   151 EFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQLTSRLKIAHRHGLWIPTLPITTII 215
            .|..::|..:|.|.|::...:|||.:|:.||:|||.||:|:..|:.....:.|.   ..|:..::
Mouse   166 TFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGF---AAPLGGLV 227

  Fly   216 P 216
            |
Mouse   228 P 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	20/52 (38%)
Pitx3	XP_006526827.1	Homeobox	152..205	CDD:365835	21/52 (40%)
		PTZ00395	<228..>322	CDD:185594	1/1 (100%)
		OAR	344..361	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910