DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and DLX5

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_005212.1	Gene:	DLX5 / 1749	HGNCID:	2918	Length:	289	Species:	Homo sapiens

Alignment Length:	176	Identity:	50/176 - (28%)
Similarity:	79/176 - (44%)	Gaps:	39/176 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DSILSTSEAHSSQNSLPKDNTNVTSSDISK-LYAFSFTQEGNNKTPLTNFDLCQGHPRRLPITFD 97
            :|..:.|:.:|.....|....:.||:...| |..:.:...|.|.:.
Human    39 ESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSA------------------- 84

  Fly    98 GSTVSRFVWRTESILPSY---------ITNSTNLQEKQLRK---RFTD------RKPRQAYSASQ 144
            ||..:: .:...|...||         :.::||..||::.:   |..:      ||||..||:.|
Human    85 GSYPAK-AYADYSYASSYHQYGGAYNRVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQ 148

  Fly   145 LERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKK 190
            |..|:..|...:||::.:|.||:.||.||:.|||.||||:|:|.||
Human   149 LAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	26/52 (50%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		2/9 (22%)
		DLL_N	32..118	CDD:315147	17/98 (17%)
		Homeobox	140..193	CDD:306543	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..251
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910