DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and Hlx

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_032276.1	Gene:	Hlx / 15284	MGIID:	96109	Length:	476	Species:	Mus musculus

Alignment Length:	174	Identity:	47/174 - (27%)
Similarity:	72/174 - (41%)	Gaps:	30/174 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 HSSQNSLPKDNTNVTSSDISKLYAFSF---TQEGNNKTPLTNFDLCQGHPRRLPITFDGSTVSRF 104
            ||  .|.|..::......|.::.:..|   .:|||....||:. |..|.|..:.:.....:..:|
Mouse   159 HS--GSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSL-LTGGRPAGVHLAGLQPSAGQF 220

  Fly   105 ------VWRTESILPSYITNSTNLQEKQLRKRF--------TDRKP----------RQAYSASQL 145
                  :....:||....:|..|..:.|.:..|        .|..|          |..:|..|.
Mouse   221 FASLDPISEASAILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQR 285

  Fly   146 ERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWK 189
            :.||..|.:.||::...|.:|:..|.||:.|||.||||||.||:
Mouse   286 KGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWR 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	24/62 (39%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	120..169		4/11 (36%)
		COG5576	224..>341	CDD:227863	32/106 (30%)
		Homeobox	276..329	CDD:278475	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..401		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	413..476
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810