DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and CUX1

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	XP_005250207.1	Gene:	CUX1 / 1523	HGNCID:	2557	Length:	1604	Species:	Homo sapiens

Alignment Length:	83	Identity:	20/83 - (24%)
Similarity:	37/83 - (44%)	Gaps:	6/83 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 SILPSYITNSTNLQEKQLRKRFTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTE 174
            |:...|...::...:.||      :|||...:..:.|.|:..:....|.|.....:|:..|:|..
Human  1326 SVGTEYSQGASPQPQHQL------KKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKT 1384

  Fly   175 VQVKTWFQNRRTKWKKQL 192
            ..|..||.|.|::.:::|
Human  1385 STVINWFHNYRSRIRREL 1402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	14/52 (27%)
CUX1	XP_005250207.1	Smc	<106..464	CDD:224117
		CUT	647..720	CDD:367059
		PHA03247	846..>1032	CDD:223021
		CUT	1038..1106	CDD:367059
		CUT	1221..1294	CDD:367059
		Homeobox	1346..1400	CDD:365835	14/53 (26%)
		PRK12678	1404..>1493	CDD:237171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910