DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34031 and Rax

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_446130.1	Gene:	Rax / 114213	RGDID:	620371	Length:	342	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	84/204 - (41%)	Gaps:	46/204 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SRLNSCIEKSIQTKKKGKLGAFSIDSILSTSEA-HSSQNSLPKDNTNVTSSDISKLYAFSFTQEG 73
            |||:|.         :..||....|.||.|..| .||:.|..:|......|...|..|     .|
  Rat    30 SRLHSI---------EAILGFTKEDGILDTFPAERSSRGSKERDPRLGARSACPKAPA-----GG 80

  Fly    74 NNKTP------LTNFDL---C----QGHPRRLPITFDGSTVSRFVWRTESILPSYITNSTNLQEK 125
            :..:|      :..|:.   |    ||..|..|    |..|.          |:  ...:.|.|:
  Rat    81 SESSPPAAPGLVPEFEATRPCYPKEQGEARPSP----GLPVG----------PA--AGDSKLSEE 129

  Fly   126 QLRKRFTDRKPRQAYSASQLERLENEFNLDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKK 190
            :...:...|:.|..::..||..||..|....|..|..|.||:..::|.||:|:.||||||.||::
  Rat   130 EEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRR 194

  Fly   191 QLTSRLKIA 199
            |  .:|:::
  Rat   195 Q--EKLEVS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	22/52 (42%)
Rax	NP_446130.1	Octapeptide motif	33..40		1/15 (7%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..141		23/112 (21%)
		Homeobox	141..193	CDD:278475	22/51 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..295
		OAR	316..331	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910