DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34031 and pbx2

DIOPT Version :9

Sequence 1:	NP_001246894.1	Gene:	CG34031 / 3885665	FlyBaseID:	FBgn0054031	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001122133.1	Gene:	pbx2 / 100101713	XenbaseID:	XB-GENE-484669	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	47/189 - (24%)
Similarity:	79/189 - (41%)	Gaps:	12/189 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 NSCIEKSIQTKKKGKLGAFSIDSILSTSEAHSSQNSLPKDNTNVTSSDISKLYAFSFT--QEGNN 75
            |..:.:.:...:||. |:.:..:..:.|...|..||:...:.....|.|.::|.....  ::..|
Frog   114 NMLLAEGVAGPEKGG-GSAAAAAAAAASGGVSPDNSIEHSDYRNKLSQIRQIYHAELEKYEQACN 177

  Fly    76 KTPLTNFDLCQGHPRRLPITFDGSTVSRFV---WRTESILPSYITNSTNLQEKQLRKRFTD-RKP 136
            :......:|.:...|..||:  ...:.|.|   .|..|.:...:..||......||.||.| |:.
Frog   178 EFTTHVMNLLREQSRTRPIS--PKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRK 240

  Fly   137 RQAYSASQLERLENEFN---LDKYLSVSKRVELSKSLSLTEVQVKTWFQNRRTKWKKQL 192
            |:.:|....|.|...|.   .:.|.|...:.||:|...:|..||..||.|:|.::||.:
Frog   241 RRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNI 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34031	NP_001246894.1	Homeobox	136..189	CDD:278475	17/55 (31%)
pbx2	NP_001122133.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		PBC	44..236	CDD:367661	26/124 (21%)
		homeodomain	238..298	CDD:238039	19/59 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	353..422
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910