DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34002 and CLEC18B

DIOPT Version :9

Sequence 1:	NP_001034029.2	Gene:	CG34002 / 3885644	FlyBaseID:	FBgn0054002	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001011880.2	Gene:	CLEC18B / 497190	HGNCID:	33849	Length:	455	Species:	Homo sapiens

Alignment Length:	216	Identity:	52/216 - (24%)
Similarity:	79/216 - (36%)	Gaps:	53/216 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 LILNHHNTYRDIVAGGQMHRLPIAARMLKLKWDHELALLATILVKRCDLQPTDHCISTEEFSSPS 135
            |:|:.||..|..|.       |.||.|.:|.|...||.||......|.       |.|...:|..
Human    50 LLLSLHNRLRSWVQ-------PPAADMRRLDWSDSLAQLAQARAALCG-------IPTPSLASGL 100

  Fly   136 YHAV---YNK--FKAKEDTFRIVRSQLNAWY---DQYKHVSSSSLIDGLSTAKKEIGHFLRMIVG 192
            :..:   :|.  ..|...:|..|   ::.|:   .:|.|.:.....:...|      |:.:::..
Human   101 WRTLQVGWNMQLLPAGLASFVEV---VSLWFAEGQRYSHAAGECARNATCT------HYTQLVWA 156

  Fly   193 PSNRLGCAIASIEKGGWTHQWLACLYSCSPQKNSLLYEYSG------KPGVY---CTTGINGKFQ 248
            .|::|||.......|....:...|.|  ||..|   :|.:|      |.|.:   ||..::|.|:
Human   157 TSSQLGCGRHLCSAGQTAIEAFVCAY--SPGGN---WEVNGKTIIPYKKGAWCSLCTASVSGCFK 216

  Fly   249 ------NLCNDTEPVKDCMHS 263
                  .||.  .|...|..|
Human   217 AWDHAGGLCE--VPRNPCRMS 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34002	NP_001034029.2	SCP_euk	69..219	CDD:240180	35/155 (23%)
CLEC18B	NP_001011880.2	SCP_euk	50..183	CDD:240180	36/157 (23%)
CLEC18B	NP_001011880.2	CLECT	310..443	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750