DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34002 and PI16

DIOPT Version :9

Sequence 1:	NP_001034029.2	Gene:	CG34002 / 3885644	FlyBaseID:	FBgn0054002	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	204	Identity:	49/204 - (24%)
Similarity:	82/204 - (40%)	Gaps:	51/204 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 KKLILNHHNTYRDIVAGGQMHRLPIAARMLKLKWDHELALLATILVKRCDLQPTDHCISTEEFSS 133
            |:|::..||.||..|:       |.|:.||.::||.|||..|....::|...
Human    33 KRLMVELHNLYRAQVS-------PTASDMLHMRWDEELAAFAKAYARQCVWG------------- 77

  Fly   134 PSYHAVYNKFKAK--EDTFRI------VRSQLNAWYDQYKHVSSSSLIDGLSTAKKEIGHFLRMI 190
                  :||.:.:  |:.|.|      |...:..|:.:.:|.:.|:   ...:..:..||:.:::
Human    78 ------HNKERGRRGENLFAITDEGMDVPLAMEEWHHEREHYNLSA---ATCSPGQMCGHYTQVV 133

  Fly   191 VGPSNRLGCAIASIEKGGWTH----QWLACLYSCSPQ---KNSLLYEYSGKPGVYCTTGINGKFQ 248
            ...:.|:||.....||.....    :.|.|.|  .|.   |....|: .|.|...|.:|.:.| .
Human   134 WAKTERIGCGSHFCEKLQGVEETNIELLVCNY--EPPGNVKGKRPYQ-EGTPCSQCPSGYHCK-N 194

  Fly   249 NLCNDTEPV 257
            :||   ||:
Human   195 SLC---EPI 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34002	NP_001034029.2	SCP_euk	69..219	CDD:240180	36/161 (22%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	37/163 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.780