DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33966 and SFH5

DIOPT Version :9

Sequence 1:	NP_001033984.1	Gene:	CG33966 / 3885642	FlyBaseID:	FBgn0053966	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_012390.1	Gene:	SFH5 / 853296	SGDID:	S000003681	Length:	294	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	44/222 - (19%)
Similarity:	78/222 - (35%)	Gaps:	58/222 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 NVDVDKALEIFRLGTIVILPRPLNDNGPRLALLRMACYDPSKYTLQEVNRAAGLMQQIMLDEDDV 152
            |.|.:|....:.|...::..:.|..|..:....|:...:.....|...:.....|.|:. |...|
Yeast   115 NGDANKKAVTWNLYGQLVKKKELFQNVDKFVRYRIGLMEKGLSLLDFTSSDNNYMTQVH-DYKGV 178

  Fly   153 AIVNGLISILDLSNVTTGHFLQMSPS--FAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIK 215
            ::......|.:.|....|.|.:..|.  :||                 :|:|.|..|..::::||
Yeast   179 SVWRMDSDIKNCSKTVIGIFQKYYPELLYAK-----------------YFVNVPTVFGWVYDLIK 226

  Fly   216 PMMSKKQQGRLYV--HGSKWEALYNQIPKQYL---PVE-YGGENGSIPELLQQWEQRILAYRNYW 274
            ..:.:..:.:..|  .|||.        .|||   |.| |||
Yeast   227 KFVDETTRKKFVVLTDGSKL--------GQYLKDCPYEGYGG----------------------- 260

  Fly   275 EEEKNYGTDESLRVGQPVDFESLFGLQ 301
            :::||..|.:::....|.:: .|:.||
Yeast   261 KDKKNNLTKQNVTNVHPTEY-GLYILQ 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024
CG33966	NP_001033984.1	SEC14	96..252	CDD:238099	33/163 (20%)
SFH5	NP_012390.1	SEC14	101..263	CDD:214706	37/196 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900