Protein Alignment CG33966 and TTPA

DIOPT Version :9

• Sequence 1: NP_001033984.1
• Gene: CG33966 / 3885642
• FlyBaseID: FBgn0053966
• Length: 310
• Species: Drosophila melanogaster
• Sequence 2: NP_000361.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 278
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 79/268 - (29%)
• Similarity: 141/268 - (52%)
• Gaps: 11/268 - (4%)

  Fly    12 QKTAIENLNEVPNK---LDDDIAALRDWIKQQ--PHLKARTDDQFLVNFLRGCKFSLERTKSKID 71
            |.:|...||.:|:.   |...:||||...::.  |.......|.||:.|||...|.|:.....:.
Human     7 QPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLK 71

  Fly    72 RFYTLRTKYPEFYLGHNVDVDKALEIFRLGTIVILPRPLNDNGPRLALLRMACYDPSKYTLQEVN 136
            .:|..|.:.||  :..::.....:.:.:.|...:| |..:..|.::.:.|:|.:||..:|..:|.
Human    72 NYYKWRAECPE--ISADLHPRSIIGLLKAGYHGVL-RSRDPTGSKVLIYRIAHWDPKVFTAYDVF 133

  Fly   137 RAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMSPSFAKKMTVFQEEALPLRPQGIHFI 201
            |.:.:..::::.|.:.. .||:.:|.||......|..|::||.|||:.....::.||:.:|||.|
Human   134 RVSLITSELIVQEVETQ-RNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLI 197

  Fly   202 NTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKW-EALYNQIPKQYLPVEYGGENGSIPELLQQWEQ 265
            |.|..|..:|:||||.:::|.:.|:::||:.: ::|....| ..||:|||||..|:.::.|:|..
Human   198 NEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGEEFSMEDICQEWTN 261

  Fly   266 RILAYRNY 273
            .|:...:|
Human   262 FIMKSEDY 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	13/43 (30%)
		SEC14	96..252	CDD:238099	49/156 (31%)
TTPA	NP_000361.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/12 (42%)
		CRAL_TRIO_N	<40..73	CDD:215024	9/32 (28%)
		CRAL_TRIO	99..248	CDD:395525	49/151 (32%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	208..211		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920