DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33966 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001033984.1	Gene:	CG33966 / 3885642	FlyBaseID:	FBgn0053966	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	336	Identity:	71/336 - (21%)
Similarity:	127/336 - (37%)	Gaps:	98/336 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LNEVPNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKIDRFYTLRTKYPEF 83
            :.::..|.::.:|..|:.::.........||.||:.:||...|.|:::::.:       .|:.||
Mouse     5 VGDLSPKQEEALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAML-------RKHVEF 62

  Fly    84 YLGHNVDVDKAL-----EIFR---------------------LGTIVILPRPLNDNG-----PRL 117
              ....|:||.:     |:.:                     :|       ||:..|     .:.
Mouse    63 --RKQKDIDKIISWQPPEVIQQYLSGGRCGYDLDGCPVWYDIIG-------PLDAKGLLFSASKQ 118

  Fly   118 ALLRMACYDPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMS-PSFAK 181
            .|||....| .:..|||.     :.|...|.:.    :..:..|.|...:...|..:.: .::.:
Mouse   119 DLLRTKMRD-CELLLQEC-----IQQTTKLGKK----IETITMIYDCEGLGLKHLWKPAVEAYGE 173

  Fly   182 KMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKW-EALYNQIPKQYL 245
            .:|:| ||..|...:.:..:..|..|...:|:|||.:|:..:.::.|.|:.| |.|...|....|
Mouse   174 FLTMF-EENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQL 237

  Fly   246 PVEYGGE----------------NGSIP-------ELLQQWEQRILAYRNYWEEEKNYGTDESLR 287
            ||||||.                .|.||       ::.||:|..:...|         |:...
Mouse   238 PVEYGGTMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHTVQVSR---------GSSHQ-- 291

  Fly   288 VGQPVDFESLF 298
                |::|.||
Mouse   292 ----VEYEILF 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	10/41 (24%)
CG33966	NP_001033984.1	SEC14	96..252	CDD:238099	41/183 (22%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	10/52 (19%)
		SEC14	76..244	CDD:214706	41/185 (22%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810