DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33966 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001033984.1	Gene:	CG33966 / 3885642	FlyBaseID:	FBgn0053966	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001121197.1	Gene:	Sec14l5 / 665119	MGIID:	3616084	Length:	696	Species:	Mus musculus

Alignment Length:	352	Identity:	67/352 - (19%)
Similarity:	123/352 - (34%)	Gaps:	106/352 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NKLDDD----------------IAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKIDR 72
            :|||.|                :..||.|: |:.|......|:.::.|||...|.|::.:..:.:
Mouse   224 DKLDADYIERCLGHLSPMQESCLVQLRHWL-QETHKGKIPKDEHILRFLRARDFHLDKARDMLCQ 287

  Fly    73 FYTLRTKY---------------PEFYLG--HNVDVD-KALEIFRLGTIVILPRPLNDNGPRLAL 119
            ..:.|.::               .|||.|  |..|:| :.|.|.|||.:
Mouse   288 SLSWRKQHQVDLLLQTWRPPPPLQEFYAGGWHYQDIDGRPLYILRLGQM---------------- 336

  Fly   120 LRMACYDPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNG-----------LISILDLSNVTTGHFL 173
                   .:|..::.|...|.|...:.::|:......|           ...:|||..:...|..
Mouse   337 -------DTKGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLW 394

  Fly   174 QMSPSFAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVH-GSKWE--- 234
            :.......:|....|:..|.....:..:..|..|..::.::.|.:::..:.:..:: ||.::
Mouse   395 RPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPG 459

  Fly   235 ALYNQIPKQYLPVEYGGEN-------GSIP-------------ELLQQWEQRILAYRNYWEEEKN 279
            .|.:.:.|..:|...|||:       |.:|             :.||||.:      .|......
Mouse   460 GLVDYLDKDVIPDFLGGESVCNVPEGGMVPKSLYLTEEEQEQADQLQQWSE------TYHSASVL 518

  Fly   280 YGTDESLRV----GQPV---DFESLFG 299
            .||...:.:    |:.|   ||:.|.|
Mouse   519 RGTPYEVAMEIPEGESVITWDFDILRG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	11/41 (27%)
CG33966	NP_001033984.1	SEC14	96..252	CDD:238099	26/170 (15%)
Sec14l5	NP_001121197.1	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	243..288	CDD:215024	11/45 (24%)
		SEC14	306..479	CDD:214706	36/195 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900