Protein Alignment CG33966 and Ttpa

DIOPT Version :9

• Sequence 1: NP_001033984.1
• Gene: CG33966 / 3885642
• FlyBaseID: FBgn0053966
• Length: 310
• Species: Drosophila melanogaster
• Sequence 2: NP_056582.1
• Gene: Ttpa / 50500
• MGIID: 1354168
• Length: 278
• Species: Mus musculus
• Alignment Length: 278
• Identity: 83/278 - (29%)
• Similarity: 144/278 - (51%)
• Gaps: 14/278 - (5%)

  Fly     1 MPAIRPLSPELQKTAIENLNEVPNK---LDDDIAALRDWIKQQ--PHLKARTDDQFLVNFLRGCK 60
            |..:|| .|.:.|    .|||:|:.   |...:|.||..:::.  |.......|.||:.|||...
Mouse     1 MAEMRP-GPLVGK----QLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARD 60

  Fly    61 FSLERTKSKIDRFYTLRTKYPEFYLGHNVDVDKALEIFRLGTIVILPRPLNDNGPRLALLRMACY 125
            |.|:.....:..:|..|.:.||  |..::.....|.:.:.|...:| |..:..|.|:.:.|:|.:
Mouse    61 FDLDLAWRLMKNYYKWRAECPE--LSADLRPRSILGLLKAGYHGVL-RSRDSTGSRVLIYRIAYW 122

  Fly   126 DPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMSPSFAKKMTVFQEEA 190
            ||..:|..:|.|.:.:..::::.|.:.. .||:.:|.||......|..|::||.|||:.....::
Mouse   123 DPKVFTAYDVFRVSLITSELIVQEVETQ-RNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDS 186

  Fly   191 LPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKWEALYNQIPKQYLPVEYGGENGS 255
            .||:.:|||.||.|..|..:|:||||.:::|.:.|:::||:.:::...|.....||.||||:..|
Mouse   187 FPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFS 251

  Fly   256 IPELLQQWEQRILAYRNY 273
            :.::.|:|...|:...:|
Mouse   252 MEDICQEWTNFIMKSEDY 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	12/43 (28%)
		SEC14	96..252	CDD:238099	49/155 (32%)
Ttpa	NP_056582.1	CRAL_TRIO_N	25..73	CDD:215024	12/47 (26%)
		CRAL_TRIO	99..248	CDD:279044	49/150 (33%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W67	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W68	208..211		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920