DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33966 and SEC14L3

DIOPT Version :9

Sequence 1:NP_001033984.1 Gene:CG33966 / 3885642 FlyBaseID:FBgn0053966 Length:310 Species:Drosophila melanogaster
Sequence 2:XP_011528430.1 Gene:SEC14L3 / 266629 HGNCID:18655 Length:412 Species:Homo sapiens


Alignment Length:341 Identity:69/341 - (20%)
Similarity:125/341 - (36%) Gaps:99/341 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LSPELQKTAI---ENLNEV----PNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLE 64
            |||:..:|..   ||:.:|    ||                      .||.||:.:||...|.|:
Human     8 LSPKQAETLAKFRENVQDVLPALPN----------------------PDDYFLLRWLRARNFDLQ 50

  Fly    65 RTKSKIDRFYTLRTKYPEFYLGHNVDVD--------KALEIFRLGTIVILPR-----------PL 110
            ::::       |..||.||  ...:|:|        :.::.:..|.:....|           ||
Human    51 KSEA-------LLRKYMEF--RKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPL 106

  Fly   111 NDNGPRLALLRMACYDPSKYTLQEVNRAAGLMQQIMLDEDDVAI------VNGLISILDLSNVTT 169
            :   |:..|..:...|..|..:::..|        :|.|.|:..      :..::.|.|...:..
Human   107 D---PKGLLFSVTKQDLLKTKMRDCER--------ILHECDLQTERLGKKIETIVMIFDCEGLGL 160

  Fly   170 GHFLQMSPSFAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKW- 233
            .||.:......::.....||..|...:.:..:.....|...:|::||.:|:..:.::.|.|:.| 
Human   161 KHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWK 225

  Fly   234 EALYNQIPKQYLPVEYGGE----------------NGSIPELLQQWEQRILAYRNYWEEEKNYGT 282
            |.|...|..:.||.::||.                .|.||:.:...:|....|.:  ..:.|.|:
Human   226 EGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEH--SVQINRGS 288

  Fly   283 DESLRVGQPVDFESLF 298
            ...      |::|.||
Human   289 SHQ------VEYEILF 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33966NP_001033984.1 CRAL_TRIO_N 30..72 CDD:215024 8/41 (20%)
SEC14 96..252 CDD:238099 33/173 (19%)
SEC14L3XP_011528430.1 CRAL_TRIO_N 13..59 CDD:215024 15/74 (20%)
SEC14 76..245 CDD:214706 34/179 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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