DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33966 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001033984.1	Gene:	CG33966 / 3885642	FlyBaseID:	FBgn0053966	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	72/337 - (21%)
Similarity:	129/337 - (38%)	Gaps:	100/337 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LNEVPNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKIDRFYTLRTKYPEF 83
            :.::..|.::.:|..|:.::.........||.||:.:||...|.|:::::.:       .|:.||
  Rat     5 VGDLSPKQEEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAML-------RKHVEF 62

  Fly    84 YLGHNVDVDKAL-----EIFR---------------------LGTIVILPRPLNDNG-----PRL 117
              ....|:||.:     |:.:                     :|       ||:..|     .:.
  Rat    63 --RKQKDIDKIISWQPPEVIQQYLSGGRCGYDLDGCPVWYDIIG-------PLDAKGLLFSASKQ 118

  Fly   118 ALLRMACYDPSKYTLQE-VNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMS-PSFA 180
            .|||....| .:..||| .::.|.|.::|          ..:..|.|...:...|..:.: .::.
  Rat   119 DLLRTKMRD-CELLLQECTHQTAKLGKKI----------ETITMIYDCEGLGLKHLWKPAVEAYG 172

  Fly   181 KKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKW-EALYNQIPKQY 244
            :.:|:| ||..|...:.:..:..|..|...:|:|||.:|:..:.::.|.|:.| |.|...|....
  Rat   173 EFLTMF-EENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQ 236

  Fly   245 LPVEYGGE----------------NGSIP-------ELLQQWEQRILAYRNYWEEEKNYGTDESL 286
            |||||||.                .|.||       ::.||:|..:...|         |:...
  Rat   237 LPVEYGGTMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHSVQISR---------GSSHQ- 291

  Fly   287 RVGQPVDFESLF 298
                 |::|.||
  Rat   292 -----VEYEILF 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	10/41 (24%)
CG33966	NP_001033984.1	SEC14	96..252	CDD:238099	42/184 (23%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	10/52 (19%)
		SEC14	76..244	CDD:214706	42/186 (23%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810