Protein Alignment CG33993 and SH2D5

DIOPT Version :9

• Sequence 1: NP_001033991.1
• Gene: CG33993 / 3885637
• FlyBaseID: FBgn0053993
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001096631.1
• Gene: SH2D5 / 400745
• HGNCID: 28819
• Length: 423
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 88/335 - (26%)
• Similarity: 120/335 - (35%)
• Gaps: 65/335 - (19%)

  Fly    76 RQQPHPHSHSHPHPHPQLQRRPVEQLHLL--HSHHDVQELSGQEHPHPQPGSHPHPHHLRSPSSE 138
            |....|.|....|.....|...|:.||||  .|......|.     ||:..:.|.|
Human   109 RNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQ-----HPEERAQPEP--------- 159

  Fly   139 EDNSPTEMNNCRRLVDKPPLVKRLTMGIGLLR---GTEDSRPLMHSTCGSSLTSGSG-CGSTQTI 199
                      |.....:.|| |.|:...||:|   |.:.....:|:..........| .||.:.:
Human   160 ----------CPGPTGEVPL-KPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKEL 213

  Fly   200 --SDGYVNEA-----ICEP----DKYVASKFGDSCRQSLSALESATQRLQVELPAASKKYLRETC 253
              |:|....|     .|.|    .|.:.||...|     .|....|...|::|.|      ||..
Human   214 PESEGRARHARLGNPYCSPTLVRKKAIRSKVIRS-----GAYRGCTYETQLQLSA------REAF 267

  Fly   254 SA--NSSPKLFPGHSALRLDNLSLAEQQELKGAAWFQAGIPREISLEALSRQSPGAFLVRQSSTK 316
            .|  .:.|:...|||.|.....||.|.      .|..|||.|..:|..|.|...||||:......
Human   268 PAAWEAWPRGPGGHSCLVESEGSLTEN------IWAFAGISRPCALALLRRDVLGAFLLWPELGA 326

  Fly   317 PGCFALSLRVPPPSPRVAHYLILRTQRG-YKIKGFTKEFSSLKALITHHSVMPELLPVPLTLPRP 380
            .|.:.||:|.   ...|..:.:.|...| |.::....||.||:||:.:|:|....|..||.:.|.
Human   327 SGQWCLSVRT---QCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLDMGRL 388

  Fly   381 PSTRSQRSQG 390
            ..|..::..|
Human   389 NPTYEEQDCG 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33993	NP_001033991.1	SH2	286..364	CDD:198173	26/78 (33%)
SH2D5	NP_001096631.1	PTB_tensin-related	23..150	CDD:269979	12/45 (27%)
		SH2	296..372	CDD:198173	26/78 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	392..423		1/7 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343821at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920