DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33993 and CG10479

DIOPT Version :9

Sequence 1:	NP_001033991.1	Gene:	CG33993 / 3885637	FlyBaseID:	FBgn0053993	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001261458.1	Gene:	CG10479 / 38674	FlyBaseID:	FBgn0035656	Length:	379	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	82/254 - (32%)
Similarity:	116/254 - (45%)	Gaps:	59/254 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 STCGSSLTSGS----------------GC-GSTQTISDGYVNEAICEPDKYVASKFGDSCRQSLS 228
            |:.|||.||.|                .| .|:|..||....|   |.|:       ::...|.:
  Fly   144 SSTGSSSTSSSSPTTPKRSPQKSLLSLNCWQSSQPSSDSNPEE---EQDE-------EAEEDSDA 198

  Fly   229 ALESATQRLQVELPAASKKYLRETCSANSSPKLFPGH-SALRLDNLSLAEQQELKGAAWFQAGIP 292
            .:....|.|....|....|..|      ::| ||..: ||.:..:....|:.||....|:|..|.
  Fly   199 GISDCCQLLAENSPNTMSKRRR------AAP-LFTRYISANQNSDDDEDEEPELLACPWYQPRIT 256

  Fly   293 REISLEALSRQSPGAFLVRQSSTKPGCFALSLRVPPPSPRVAHYLILRTQ-RGYKIKGFTKEFSS 356
            .:.:||.|.:.:||:||:|:|:  |..|.|.||: ..:.:|..|.:..|: :.|::||..|:|:|
  Fly   257 AKAALEHLQQATPGSFLLRRST--PRHFELVLRL-ERNNKVKTYPVQSTRNQMYRLKGAKKQFTS 318

  Fly   357 LKALITHHSVMPELLPVPLTLPR------PPSTRSQRSQGAYAGGTGNGGADFEMYGSL 409
            |||||||||||.|.||:.|.:||      |.|.|       ||.       |||...||
  Fly   319 LKALITHHSVMAEQLPLVLDMPRERHVVKPSSVR-------YAD-------DFEPLESL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33993	NP_001033991.1	SH2	286..364	CDD:198173	32/78 (41%)
CG10479	NP_001261458.1	SH2	249..326	CDD:198173	32/79 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343821at33208
OrthoFinder	1	1.000	-	-		FOG0007616
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45734
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020