Protein Alignment Egfrap and Sh2d5

DIOPT Version :10

• Sequence 1: NP_001033991.1
• Gene: Egfrap / 3885637
• FlyBaseID: FBgn0053993
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001418136.1
• Gene: Sh2d5 / 366489
• RGDID: 1305952
• Length: 429
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 77/301 - (25%)
• Similarity: 109/301 - (36%)
• Gaps: 74/301 - (24%)

  Fly   116 QEHPHPQPGSHP--------------HPHHLRSPSSEEDNSPTEMNNCRRLVDKPPLVKRLTMGI 166
            :|...|:|...|              .|..:|.|.|.:..|    .|...||.    .:||. ..
  Rat   152 EERAQPEPSLVPGGDMSLKPLCSPGVAPALVREPFSRDQLS----QNVHALVS----FRRLP-AE 207

  Fly   167 GLLRGTEDSRPLMHSTCGSSLTSGSGCGSTQTISDGYVNEAICEP----DKYVASKFGDSCRQSL 227
            |||           .:.|..|....|.|.|:.|..|   ...|.|    .|.:.||...|
  Rat   208 GLL-----------GSNGKELPEPEGRGGTRHIRLG---NPYCSPTLVRKKAIRSKVIRS----- 253

  Fly   228 SALESATQRLQVEL------PAASKKYLRETCSANSSPKLFPGHSALRLDNL-SLAEQQELKGAA 285
            .|....|...|::|      |||.:.:.|.           ||..:..::|. ||.|.      .
  Rat   254 GAYRGCTYETQLQLSAREAFPAAWEAWPRG-----------PGSPSCLVENEGSLTEN------I 301

  Fly   286 WFQAGIPREISLEALSRQSPGAFLVRQSSTKPGCFALSLRVPPPSPRVAHYLILRTQRG-YKIKG 349
            |..||:.|..:|..|.|...||||:.......|.::||:|.   ...|..:.:.|...| |.::.
  Rat   302 WAFAGLSRSCALALLRRDVHGAFLLWPEPGTSGQWSLSVRT---QCGVVSHQVFRNHLGRYCLEH 363

  Fly   350 FTKEFSSLKALITHHSVMPELLPVPLTLPRPPSTRSQRSQG 390
            ...||.||:||:..|:.|...|..||::.|...|..::..|
  Rat   364 LPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDSG 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egfrap	NP_001033991.1	SH2	286..364	CDD:198173	25/78 (32%)
Sh2d5	NP_001418136.1	PTB_tensin-related	23..150	CDD:269979
		SH2	302..378	CDD:198173	25/78 (32%)