DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG33993 and Tns4

DIOPT Version :9

Sequence 1:NP_001033991.1 Gene:CG33993 / 3885637 FlyBaseID:FBgn0053993 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001020052.1 Gene:Tns4 / 303517 RGDID:1310402 Length:718 Species:Rattus norvegicus


Alignment Length:453 Identity:98/453 - (21%)
Similarity:152/453 - (33%) Gaps:151/453 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 IMQDIRLRLEPQHSKATFISSSSASSSSSQTAETTLIETAEKSPASEA-AAGTVTTTSPQHFFHH 65
            :.:||........:::...|.:....||..|..:    .:...|..|: |:|:...|        
  Rat   182 LSRDIPRETRSSSNESLIFSGNQGRGSSPHTPSS----LSNSIPCRESRASGSPLAT-------- 234

  Fly    66 HHPPAHPHPPRQQPHPHSHSHPHPHPQ-------LQRRPVEQLHLLHSHHDVQELSGQEHPHPQP 123
              ||......|.             ||       |...||..:..:..       |.|..||...
  Rat   235 --PPGWEKGLRA-------------PQWGSRVSTLSASPVSDISYVFG-------SNQSLPHSSL 277

  Fly   124 GSHPHPHHLRSPSSEEDNSPTEMNNCRRLVDKPPLVKRLTMGIGLLRGTE---DSRPLMHSTCGS 185
            .|:|       |||....||...::....:|:         |...:|.::   .|.|::      
  Rat   278 SSYP-------PSSRSLGSPASSSSSLHSLDR---------GSQCVRSSDAQVPSNPIV------ 320

  Fly   186 SLTSGSGCGSTQTISDGYVNEAICEPDKYVASKFGDSCRQSL-------------------SALE 231
                  |.|..|.:           |...||.:...||..|:                   |...
  Rat   321 ------GMGQPQAV-----------PSTPVAKEQASSCPPSVTNSMADIPIVLINGNPEPQSPPA 368

  Fly   232 SATQRLQ--VELPAASKKYLRETCSANSS--------PKLFPGH--SALRLDNLSLAE------- 277
            ..|.|.|  |:..|.|..:|   |.|..|        |...|.|  .|.:..:.:|.:       
  Rat   369 QQTPRYQDSVQSRATSPSHL---CQATKSHSKTLPDVPLTSPSHLCQATKSHSKTLPDVPLTASP 430

  Fly   278 -------QQELK-----GAAWFQAGIPREISLEALSRQSPGAFLVRQSSTKPGCFALSLRV---P 327
                   |..:|     ...|.:..|.||.::..|..:.||.|::|.||:..|.|.|:|:|   |
  Rat   431 ESPAKDMQPTMKFVMDTSKYWLKPSITREQAINLLRTEKPGTFVIRDSSSYRGSFGLALKVQETP 495

  Fly   328 PPSPR---------VAHYLILRTQRGYKIKGFTKE--FSSLKALITHHSVMPELLPVPLTLPR 379
            ..:|.         :.|:|:..:.:|..:||..:|  |.||.|.:..||:|...||..||:|:
  Rat   496 ASAPNRPGEDSTDFIRHFLVESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQ 558

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33993NP_001033991.1 SH2 286..364 CDD:198173 28/91 (31%)
Tns4NP_001020052.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 188..244 11/69 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 272..437 39/206 (19%)
SH2 447..560 CDD:301589 36/112 (32%)
PTB_tensin 583..712 CDD:269924
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166351063
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45734
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.940

Return to query results.
Submit another query.