Protein Alignment CG33993 and shc-2

DIOPT Version :9

• Sequence 1: NP_001033991.1
• Gene: CG33993 / 3885637
• FlyBaseID: FBgn0053993
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_494915.2
• Gene: shc-2 / 173860
• WormBaseID: WBGene00020867
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 355
• Identity: 81/355 - (22%)
• Similarity: 140/355 - (39%)
• Gaps: 81/355 - (22%)

  Fly    90 HPQLQRRPVEQLHLLHSHHDVQELSGQEHPHPQPGSHPHPHHLRSPSSEEDNSPT---------- 144
            |.|..:...|..::|.:.:..|.|:.::.......|..||.:..|..:|:.::.|
 Worm   249 HCQSLKEAEEIENVLRNANQSQVLAAKQPKSAVSTSSMHPTNTASTMTEKRSASTVFLNRFLGKK 313

  Fly   145 ------EMNNCRRLVDKPPLVKRLTMGIGLLRGTEDS-RPLMHSTCGS---------SLTSGSGC 193
                  |...|:|  .:.|:....:..|..|..:..| .|...||...         .|.:...|
 Worm   314 GSQTVDESGQCKR--KRRPVSAVFSSAIHRLSSSTSSVNPKRMSTIEPQAPTREQLLQLQNQMRC 376

  Fly   194 GSTQTISDGYVNEAICEPDKYVASKFGDSCRQSLSALESATQRLQVELPAASKKYLRETCSANSS 258
            .::..:.:        ||      :..|.|..|.:...|:.        |:|......:.|.::|
 Worm   377 AASSPVPE--------EP------RPTDLCAASTTTSTSSV--------ASSSSSNGSSSSTDTS 419

  Fly   259 PKLFPGHSALRLDN--------LSLAEQQELKGAAWFQAGIPREISLEALSRQSPGAFLVRQSST 315
            |......:||..|.        :..|...:|...::|.....::..:..|:.|..|||::|.|.:
 Worm   420 PVPPAPQTALVYDEKLGEWIYPIDQALMTQLDNCSYFVGQPTKDSMVYNLNTQPEGAFVIRYSES 484

  Fly   316 KPGCFALSLRVP---PPSPRVAHYLILRTQRGYKIK--GFTKEFSSLKALITHHSVMPELLPVPL 375
            |..|.|||:|||   .|| .::||||:|.::|:::|  ...|.|.:|:.::|||||:...||..|
 Worm   485 KSKCLALSMRVPCSHNPS-GISHYLIIRNEQGFRLKLSATKKPFPTLQMMLTHHSVLESHLPCTL 548

  Fly   376 -----------------TLPRPPSTRSQRS 388
                             |:.||..|.::.|
 Worm   549 HFVQWQKTNFKQLAAMSTVERPLRTFNRHS 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33993	NP_001033991.1	SH2	286..364	CDD:198173	29/82 (35%)
shc-2	NP_494915.2	PH-like	152..268	CDD:388408	4/18 (22%)
		SH2	454..537	CDD:198173	29/83 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343821at33208
OrthoFinder	1	1.000	-	-		FOG0007616
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850