Protein Alignment CG33993 and tns-1

DIOPT Version :9

• Sequence 1: NP_001033991.1
• Gene: CG33993 / 3885637
• FlyBaseID: FBgn0053993
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_491637.2
• Gene: tns-1 / 172215
• WormBaseID: WBGene00006508
• Length: 1354
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 128/643 - (19%)
• Similarity: 197/643 - (30%)
• Gaps: 278/643 - (43%)

  Fly    30 SQTAETTLIETAEKSPASEAAAGTVTTTS-------------PQHFFHHHHPPAH-PHPPRQQPH 80
            :|.|..|...|.::.|...|.:|:..|.:             |:::.:::...|. |.|.||:.|
 Worm   588 AQRAVITPTSTLQRRPKPPARSGSYRTLNDDAYCSDMDELCDPEYYLNYNSNTAPLPPPRRQEQH 652

  Fly    81 PHSHSHPHPHPQLQRRPV--------EQLHLLHSHHDVQELSG----QEHPHP------------ 121
            ..:.|...|..::....|        |....|.|.:.|.::.|    |:..|.
 Worm   653 AGTRSVQLPRKKMNFDAVTDPLDDVLESTKRLGSAYSVGDVRGGQQQQQEQHNASNDFNFSNTLN 717

  Fly   122 ---------------QPGSHPHPHHLRSPSSEE--DNSPTEMN------NCRRLVDKPPLVKRLT 163
                           |..:.|..||..:||.|:  |.:.|.::      ..:|.:| |.:|:|.|
 Worm   718 NTPTDYRQHYRNRNCQSVTTPRNHHFSTPSREQEADAADTWLSGKLKKVRSKRDID-PDIVRRRT 781

  Fly   164 M----------------------------GIGL-------------------------------L 169
            .                            |.||                               :
 Worm   782 QEKMLLEELKDSAANNDENQHNLPNGHARGAGLQNIDPLAEFRREEERLRNTRSPYGEERWRGRM 846

  Fly   170 RGTEDSRPLMHSTCG--SSLTSGSGCGSTQTISDGYVNEAICEP----------DKYVASKFGDS 222
            ||...:.|...|:..  :||..|:   ....:.....|:::..|          |......|...
 Worm   847 RGKPPTPPPRESSASPVNSLPRGT---PAHHMDRQRHNQSVPLPMHHRQFDEDFDVNSLFNFSHD 908

  Fly   223 CRQSLSALESATQRL-------------QVELPA-----------ASKKYLRETC---------- 253
            .||..:.||...:.|             |.:|.|           |:..|..||.
 Worm   909 PRQQSTTLERGGRSLSRGARIQDAYYASQQDLSANNRFNSGQERVAAAIYRAETAHRDMYASGTI 973

  Fly   254 ----------------------------------------------------------------- 253
                                                                             
 Worm   974 NRAETPGRYFPENSAVLERSSTPSFPVSRATPLPFHPLLYNNGERGGSGHAAGGGGGGHNGYSTM 1038

  Fly   254 -SANSSPKLFPGHSAL-RLDNLSLAEQQEL----------KGAAWFQAGIPREISLEALSRQSPG 306
             :.::||:||.|.|.| |..:::..:..|:          ....|::..|.||.::..|..:.||
 Worm  1039 NNRSASPRLFGGSSTLSRRSSVNSVDTSEIIHHHPLFVKDTSKYWYKPTISREQAINMLRDKPPG 1103

  Fly   307 AFLVRQSSTKPGCFALSLRV--PPP-------SPRVAHYLILRTQRGYKIKGFTKE--FSSLKAL 360
            .|:||.|::.||.|.|:|:|  |||       |..|.|:||..:.:|.|:||...|  |.||.||
 Worm  1104 TFVVRDSNSFPGAFGLALKVSTPPPGVNPGDGSELVRHFLIEPSPKGVKLKGCNNEPVFGSLSAL 1168

  Fly   361 ITHHSVMPELLPVPLTLP--RPPSTRSQRS-------QGA-----YAGG------TGN 398
            :..||:....||..|.||  .|.:|....|       |||     |.|.      |||
 Worm  1169 VYQHSITALALPTKLVLPDFDPAATPEHLSATQALLEQGAACNVVYVGSVDVESLTGN 1226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33993	NP_001033991.1	SH2	286..364	CDD:198173	35/88 (40%)
tns-1	NP_491637.2	PTP_tensin	46..203	CDD:350358
		SH2_Tensin_like	1079..1189	CDD:198181	42/109 (39%)
		PTB_tensin	1207..1348	CDD:269924	7/20 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45734
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010