DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir62a and Ir7c

DIOPT Version :9

Sequence 1:	NP_001033986.1	Gene:	Ir62a / 3885628	FlyBaseID:	FBgn0053971	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	565	Identity:	114/565 - (20%)
Similarity:	197/565 - (34%)	Gaps:	160/565 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RRYTRTMFLLRKQESQKDIKYFFELLW-----------KLQFRSAL--VVVAARNFYQMDPYPTV 174
            |.|.|....|.:..|......||.:::           |:.||..|  .|:....|.|.|
  Fly   101 RSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIMFRRLLNMYVLNVNVFLQRD----- 160

  Fly   175 RVIRMRRLSSYDPHH--------------VFPPAN----------RK--NFRGYRMRLPVQQDVP 213
            ..:.:.....|.|||              :..|||          ||  |..|..|.:...:..|
  Fly   161 GTVHLYTYYPYGPHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRP 225

  Fly   214 NTFWYKNRRTKAW-ELAGLGGILINQLMMHLNVTMDLF-RFEVNGSSLL---NMAALTDLIVKGK 273
            ......:.:|... .:.|:.|::...|...:|.|:.|. :.:.|...:|   |...:..::|.|:
  Fly   226 YVIIEDDPKTPGGRSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGE 290

  Fly   274 VELS--PHLYDTLQSNTSVDYSYPTQVAPRCFMIPLDNEISRSLYVFLPFSLTMWLCLLFVLLVV 336
            |.|:  ..:|...:|:..:..:..|.. |...::|....||....:..||...:|.|:| |.|:.
  Fly   291 VNLTFVCFMYSKARSDLMLPSTSYTSF-PIVLVVPSGGSISPMGRLTRPFRYIIWSCIL-VSLIF 353

  Fly   337 HFVYV------------------RRLIPDGHFWA-ILGVPGAGQVRYGNRKPVRRFSTFLI---L 379
            .||.:                  |..:|....|| :||    |...|   .|.|.|:.:::   |
  Fly   354 GFVLICLLKITALPGLRNLVLGRRNRLPFMGMWASLLG----GLALY---NPQRNFARYILVMWL 411

  Fly   380 FGIFILGQTYSTKLTSSLTVTLIRRPDNSLEELFLLPYRILVLP------------TDVYAIVD- 431
            ....||...|:.:|...|....:|.|..||.|:....|...:||            |:.:|::.
  Fly   412 LQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAVLSL 476

  Fly   432 ---------------SLGHAEQFSTKFSCTDAENFSQKRISMHPEYIYPISTIRWRFFDMQQRFL 481
                           ::...:....:|......|  ::.:::.|:   |:.|.
  Fly   477 EESLYRLRDEDDPGITVALLQPTVNQFDFRSGPN--KRHLTVLPD---PLMTA------------ 524

  Fly   482 RKKRFYFSKICHGSFPYQYQLRVDSHLKDALHRFLLHVQQAGLHDLWLDTCYRKAHRMGYLKDFS 546
                           |..:.:|..|:.|..:.|.::.:..:|     :...|||.: |..:|..|
  Fly   525 ---------------PLTFYMRPHSYFKRRIDRLIMAMMSSG-----IVARYRKMY-MDRIKRVS 568

  Fly   547 TLAELEEKLRLRPLAL----NLLVPAFSLFLCGMLGSGIAFLVEI 587
            ....||.|    ||::    .:.|....|:|..:    |.|::||
  Fly   569 KRRNLEPK----PLSIWRLSGIFVCCAGLYLVAL----IVFILEI 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir62a	NP_001033986.1	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	11/61 (18%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	57/299 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010