DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34049 and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_001033871.2	Gene:	CG34049 / 3885620	FlyBaseID:	FBgn0054049	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	158	Identity:	42/158 - (26%)
Similarity:	57/158 - (36%)	Gaps:	40/158 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KQAVLRETNKYR-----RLHNANPLKMDEKLCSYAQEWADHLADLNKLETRPNPL---YGENI-- 200
            |:.:|...||.|     :..|...:..|::|...|..||....    .|..|..|   .|:|:
Human    56 KEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCI----WEHGPTSLLVSIGQNLGA 116

  Fly   201 --MRVRRSKFSVDQILKLWYQEKYNYDYLKPG----------FNLYTGHFTQLVWRESEFLGVGV 253
              .|.|...|.|..    ||.|..:|.|..|.          ......|:||:||..:..:|..|
Human   117 HWGRYRSPGFHVQS----WYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAV 177

  Fly   254 -ACDVSSIW---------IVCNYHPPGN 271
             .|...::|         .||||.|.||
Human   178 NTCRKMTVWGEVWENAVYFVCNYSPKGN 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34049	NP_001033871.2	SCP_GAPR-1_like	146..272	CDD:240182	42/158 (27%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	38/152 (25%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820