DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34049 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_001033871.2	Gene:	CG34049 / 3885620	FlyBaseID:	FBgn0054049	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	157	Identity:	44/157 - (28%)
Similarity:	62/157 - (39%)	Gaps:	40/157 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 QAVLRETNK-----YRRLHNANPLKMDEKLCSYAQEWADHLADLNKLETRPN---PLYGENI--- 200
            |::|...||     |....|...:..|.:|...|:.||:...    .|..|.   |..|:|:
Human    63 QSILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWAESCL----WEHGPASLLPSIGQNLGAH 123

  Fly   201 -MRVRRSKFSVDQILKLWYQEKYNYDY-LKPGFNLY-----TG----HFTQLVWRESEFLGVGV- 253
             .|.|...|.|..    ||.|..::.| .:...|.|     :|    |:||:||..|..:|..:
Human   124 WGRYRPPTFHVQS----WYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVVWATSNRIGCAIN 184

  Fly   254 ACDVSSIW---------IVCNYHPPGN 271
            .|...:||         :||||.|.||
Human   185 LCHNMNIWGQIWPKAVYLVCNYSPKGN 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34049	NP_001033871.2	SCP_GAPR-1_like	146..272	CDD:240182	44/157 (28%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	40/151 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820