DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34049 and CRISP2

DIOPT Version :9

Sequence 1:	NP_001033871.2	Gene:	CG34049 / 3885620	FlyBaseID:	FBgn0054049	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	XP_005249406.1	Gene:	CRISP2 / 7180	HGNCID:	12024	Length:	278	Species:	Homo sapiens

Alignment Length:	173	Identity:	50/173 - (28%)
Similarity:	72/173 - (41%)	Gaps:	37/173 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 VLRE-TNKYRRLHNA------NPLKMD--EKLCSYAQEWADHLA------DLNKLETRPNPLYGE 198
            |.|| .||:..|..|      |.|||:  .::.:.||.||:...      :..|..||    .||
Human    36 VQREIVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRKTSTR----CGE 96

  Fly   199 NIMRVRRSKFSVDQILKLWYQEKYNYDY----LKPGFNLYTGHFTQLVWRESEFLGVGVA-C--- 255
            |:. :.....|....::.||.|..::.|    ..|  |...||:|||||..:..:|.|:| |
Human    97 NLY-MSSDPTSWSSAIQSWYDEILDFVYGVGPKSP--NAVVGHYTQLVWYSTYQVGCGIAYCPNQ 158

  Fly   256 DVSSIWIVCNYHPPGNVSEHFRENV-------LPRKFLLLKSD 291
            |....:.||.|.|......:.||.:       ..|.|.||:.:
Human   159 DSLKYYYVCQYCPAMKTYLNKREGINVWKCFLRLRHFQLLRGE 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34049	NP_001033871.2	SCP_GAPR-1_like	146..272	CDD:240182	44/145 (30%)
CRISP2	XP_005249406.1	SCP_CRISP	35..172	CDD:240183	43/142 (30%)
CRISP2	XP_005249406.1	Crisp	224..278	CDD:285731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920