DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34049 and vap-1

DIOPT Version :9

Sequence 1:	NP_001033871.2	Gene:	CG34049 / 3885620	FlyBaseID:	FBgn0054049	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	364	Identity:	68/364 - (18%)
Similarity:	108/364 - (29%)	Gaps:	141/364 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EIENKVQS-AEKCP--LQIIQ----HNDATFIG-------------------------CDSSNRD 34
            |:|.|.|. |:.||  .|...    .|.||::|                         .|..|:.
Worm    73 EMEAKAQEWADGCPSSFQTFDPTWGQNYATYMGSIADPLPYASMAVNGWWSEIRTVGLTDPDNKY 137

  Fly    35 LEKCR--------------SCLTSFC--RKPIKIYHNSRNYL----------ACEVQRSQSINSI 73
            .....              .|..:.|  :..|...:|...|:          ||
Worm   138 TNSAMFRFANMANGKASAFGCAYALCAGKLSINCIYNKIGYMTNAIIYEKGDAC----------- 191

  Fly    74 KSLPVKFPSTPNRSLNTEKDWSHGKRCLQCAAPK---------CKTSSRSSIQSKK-----LKKD 124
                     |.:....|..| |..|..|...||:         |.:.:..|.|:::     ..|.
Worm   192 ---------TSDAECTTYSD-SQCKNGLCYKAPQAPVVETFTMCPSVTDQSDQARQNFLDTHNKL 246

  Fly   125 KKSLLKEFEIYKI------PIIRRKP-IKQAVLRETNKYRRLHNANPLKMDEKLCSYAQEWA--- 179
            :.||.|..|...|      |:.::.| :|.:...|.|                    |:.||
Worm   247 RTSLAKGLEADGIAAGAFAPMAKQMPKLKYSCTVEAN--------------------ARTWAKGC 291

  Fly   180 --DHLADLNKLETRPNPLYGENIMRVRRSKF----SVDQILKLWYQEKYNYD------YLKPGFN 232
              .|.....:      |..|||:..:..:..    :.:...|.|:.|..::.      ..:..|:
Worm   292 LYQHSTSAQR------PGLGENLYMISINNMPKIQTAEDSSKAWWSELKDFGVGSDNILTQAVFD 350

  Fly   233 LYTGHFTQLVWRESEFLGVGVACDVSSIWIVCNYHPPGN 271
            ...||:||:.|..:..:|..|....:..:.||.|.|.||
Worm   351 RGVGHYTQMAWEGTTEIGCFVENCPTFTYSVCQYGPAGN 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34049	NP_001033871.2	SCP_GAPR-1_like	146..272	CDD:240182	28/141 (20%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553	17/101 (17%)
vap-1	NP_001024553.1	SCP	234..386	CDD:214553	34/177 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920