DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34049 and CRISP1

DIOPT Version :9

Sequence 1:	NP_001033871.2	Gene:	CG34049 / 3885620	FlyBaseID:	FBgn0054049	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001122.2	Gene:	CRISP1 / 167	HGNCID:	304	Length:	249	Species:	Homo sapiens

Alignment Length:	183	Identity:	46/183 - (25%)
Similarity:	75/183 - (40%)	Gaps:	47/183 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 LKKDKKSLLKEFE--IYKIPIIRRKPIKQAVLRETNKYRRLHNA----------NPLKMDEKLCS 173
            |...|||...:|.  :..:|.::.:.:            .:|||          |.|||     |
Human    19 LSMKKKSARDQFNKLVTDLPNVQEEIV------------NIHNALRRRVVPPASNMLKM-----S 66

  Fly   174 YAQEWADH---------LADLNKLETR-PNPLYGENIMRVRRSKFSVDQILKLWYQEKYNY---D 225
            :::|.|.:         :.:.|.||.| ||...||| |.:.....|...::.:||.|..::   :
Human    67 WSEEAAQNARIFSKYCDMTESNPLERRLPNTFCGEN-MHMTSYPVSWSSVIGVWYSESTSFKHGE 130

  Fly   226 YLKPGFNLYTGHFTQLVWRESEFLGVGVA-CDVSS---IWIVCNYHPPGNVSE 274
            :.....::.|.|:||:||..|..:|..:| |....   ...||:|...||..|
Human   131 WTTTDDDITTDHYTQIVWATSYLIGCAIASCRQQGSPRYLYVCHYCHEGNDPE 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34049	NP_001033871.2	SCP_GAPR-1_like	146..272	CDD:240182	38/152 (25%)
CRISP1	NP_001122.2	SCP_CRISP	39..177	CDD:240183	37/155 (24%)
CRISP1	NP_001122.2	Crisp	195..249	CDD:285731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920