Protein Alignment ppk10 and asic1a

DIOPT Version :10

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_999955.1
• Gene: asic1a / 791696
• ZFINID: ZDB-GENE-040513-2
• Length: 501
• Species: Danio rerio
• Alignment Length: 526
• Identity: 104/526 - (19%)
• Similarity: 187/526 - (35%)
• Gaps: 144/526 - (27%)

  Fly    21 LYFNNCCIHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSSIDRYYTKSTHIGIERNYIFW 85
            ::.:...:||..::.....|..:..||::..::|:.|.:.||:..| ::|.:..|:
Zfish    25 VFAHTSTLHGISHIFSYEKITAKCCLWVVFFLSSLTFLMYVCIDRI-QFYLEYPHV--------- 79

  Fly    86 NTTL----------PSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENLA--NSTYINFQ 138
             |.|          |:||:|   .||...|:...||:         |:...|.||  ||.:
Zfish    80 -TKLDEITTPVMVFPAVTIC---NLNSIRFSRITRND---------LYHAGELLALLNSRH---- 127

  Fly   139 NIPQNEQIDQIIEDI--------GLKPEHYTELIYNLTYDRTYEPNFNERIRCMDGAMFIHVRQV 195
            .:.:...:::.:.::        ..||.|:....:   |:||.....:..:.|.
Zfish   128 EVREAHLVEESVMEVLKSKTDFRSFKPRHFNMWEF---YNRTGHDIKDMLLSCQ----------- 178

  Fly   196 LTEWGLCYLGNSKLTEEYSSRYFIFGKYPEYNKYEYENIRLPYQVGS--------FFQKDTQYAL 252
                   :.|:....|::|..:..:||...:|..|....|:..:.|.        ..|:|....:
Zfish   179 -------FRGSPCRPEDFSVVFTRYGKCYTFNSGETGPPRVSVKGGMGNGLEIMLDIQQDEYLPV 236

  Fly   253 LGFKGPAIIAFAHSAFEV-MKVDSNS-------DYAYDGILYDLSTEEITAEDNLEQDTTVAMRR 309
            .|...       .|:||. :||..:|       |....|:.....|.....|..|.. .......
Zfish   237 WGESD-------ESSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLVY-LPAPWGS 293

  Fly   310 CRFPHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPNRIANPKPVCDYKTLRSCFPHHAS 374
            |:....|: .:|..|:.:.|:.:|......:.|.|.....|    ...|.|.....:.| .|.|.
Zfish   294 CKSTPPSS-DYFRAYSISACRTDCETRYLVENCNCRMVHMP----GDAPYCTPVLYKEC-AHPAL 352

  Fly   375 FFLKLYEENGKHENPAICYCEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSV----KTWPQSR- 434
            .|  |.|.:..:     |.||..|:   :|..| ..:|..|     |.|..||    |.:.:|.
Zfish   353 DF--LVETDSDY-----CSCETPCN---ITRYS-KELSFVK-----IPSKASVKYLAKKYSKSEK 401

  Fly   435 --------------------LRRQVIFSLTDLLVSIGGTAGLFLGFSVLGFVEVIYFFTIRIVFQ 479
                                :.::..:.:..||..|||..|||:|.|:|..:|:..:     :::
Zfish   402 YITENVMVLDVFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDY-----LYE 461

  Fly   480 ILGYTL 485
            ::.|.|
Zfish   462 VMKYRL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:459966	102/509 (20%)
asic1a	NP_999955.1	ENaC	23..469	CDD:273304	104/526 (20%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:Q1XA76	446..448		1/1 (100%)