Protein Alignment ppk10 and SCNN1G

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001030.2
• Gene: SCNN1G / 6340
• HGNCID: 10602
• Length: 649
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 114/613 - (18%)
• Similarity: 188/613 - (30%)
• Gaps: 232/613 - (37%)

  Fly    12 LKIVINYFVLYFNNCCIHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSSIDRYYTKSTHI 76
            :|.::.::.|..|.   ||.|.:..|...| .:.||:...:.::...:..|...:..:||.|..|
Human    25 IKELMRWYCLNTNT---HGCRRIVVSRGRL-RRLLWIGFTLTAVALILWQCALLVFSFYTVSVSI 85

  Fly    77 GIERNYIFWNTTLPSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENLANSTYINFQNIP 141
            .:.    |.....|:||:|.::....:             ..|.:|.| ||........:....|
Human    86 KVH----FRKLDFPAVTICNINPYKYS-------------TVRHLLAD-LEQETREALKSLYGFP 132

  Fly   142 QN------EQIDQIIEDIGLKPEHYTELIYNLTYDRTYEPN----FNERIRCMDGA--------M 188
            ::      |..:.:.|  |.:| .::..|..|.:|:..:..    |..|.|.:.|:        |
Human   133 ESRKRREAESWNSVSE--GKQP-RFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVM 194

  Fly   189 FIHVRQVLTEWGLCYLGNSKLTEEYSSRYFIFG--KYPEYNKYEYENIR----LPYQVGSFFQKD 247
            .|..:||: .:.||    |..|.:.::..|..|  ...|:.|..|.||.    |..::...:..:
Human   195 HIESKQVV-GFQLC----SNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAE 254

  Fly   248 TQYALLGFKGPAIIAFAHSAFE-----------------VMKVD-SNSDYAYDGILY-------- 286
            .......|.|.:..|...:.|.                 ::... ..|:|....|||
Human   255 ELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNP 319

  Fly   287 ----------------------DLSTEEITAEDNLEQDTTVAMRRCRFPHESNLTHFPF------ 323
                                  |:.||..||     ..|::.|...    ||.....|:
Human   320 FLVSSTGAKVIIHRQDEYPFVEDVGTEIETA-----MVTSIGMHLT----ESFKLSEPYSQCTED 375

  Fly   324 -------------YTRNICQQECRINLAYKICKCIPHFYPNRIANPKP----VCDYKTLRSCFPH 371
                         |:..||...|......:.|.|..:      :.|.|    .|:|:
Human   376 GSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQY------SQPLPPAANYCNYQ-------- 426

  Fly   372 HASFFLKLYEENGKHENPAICY-------------CEQNCHD-----------------SVVTMK 406
                         :|.|...||             |:..|.:                 |||:.|
Human   427 -------------QHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEK 478

  Fly   407 SMNPMSGAKQLLGGIGSAVSVKTWPQSR----------LRRQVIF---------------SLTDL 446
            .:.|                |.||.|.|          |.:.:||               |:..|
Human   479 WLLP----------------VLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEML 527

  Fly   447 LVSIGGTAGLFLGFSVLGFVEVIYFFTI 474
            |.:.||..||::..||:..:|:|..|.|
Human   528 LSNFGGQLGLWMSCSVVCVIEIIEVFFI 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	110/598 (18%)
SCNN1G	NP_001030.2	ENaC	24..630	CDD:273304	114/613 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820