Protein Alignment ppk10 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 116/611 - (18%)
• Similarity: 191/611 - (31%)
• Gaps: 237/611 - (38%)

  Fly    20 VLYFNNCCIHGFRYLTDSMLILFE----KFLWLILLIASIYFCIIVCLSSIDRYYTKSTHIGI-E 79
            |.|.:|...||      ...|:.|    |.:|.:|   ::.|..:||           ...|| .
Human    46 VWYCDNTNTHG------PKRIICEGPKKKAMWFLL---TLLFAALVC-----------WQWGIFI 90

  Fly    80 RNYIFWNTTL-----------PSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENL---- 129
            |.|:.|..::           |:||:|     |.:.| .|.:...:.....:::...||.:
Human    91 RTYLSWEVSVSLSVGFKTMDFPAVTIC-----NASPF-KYSKIKHLLKDLDELMEAVLERILAPE 149

  Fly   130 ---ANST-YINF------------QNIPQNEQIDQIIED--IGLKPEHYTELIYN---------- 166
               ||:| .:||            :..|.:..:..:..|  .||.....:|.|.|
Human   150 LSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRL 214

  Fly   167 LTYDRTYEPNFNERIRCMDGAMFIHVRQVLTEWGLCYLGN-------SKLTE-EYSSRYFI---- 219
            .:.:|| :..|..         |....|.||||.:....|       .:|.| .|.....|
Human   215 CSLNRT-QCTFRN---------FTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACL 269

  Fly   220 FGK------------YPEY-NKYEYE-----------------NIRLPYQVGSFFQKDTQYALLG 254
            ||.            ||.| |.|.:.                 .::|...:|   |:|....|..
Human   270 FGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIG---QEDYVPFLAS 331

  Fly   255 FKGPAIIAFAHSAFEVMKVDSNSDYAYD------GILYD-------------LSTEEITAEDNLE 300
            ..|..::.....::..::  ....||..      |:|.|             ::..|:..::
Human   332 TAGVRLMLHEQRSYPFIR--DEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQN--- 391

  Fly   301 QDTTVAMRRCRFPHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPNRIANPKPVCDYKTL 365
                       |..:.|.|    |:...|.:.|..:...:.|.|..:.||  :...:..|:.:.
Human   392 -----------FYSDYNTT----YSIQACLRSCFQDHMIRNCNCGHYLYP--LPRGEKYCNNRD- 438

  Fly   366 RSCFPHHASFFLKLYEENGKHENPAICYCEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSVKTW 430
               ||..|..:..|.....:.|. .|..|:::|:|:...|                  .:|:..|
Human   439 ---FPDWAHCYSDLQMSVAQRET-CIGMCKESCNDTQYKM------------------TISMADW 481

  Fly   431 P-------------QSR-------LRRQVIFSLTD--------------------LLVSIGGTAG 455
            |             |.|       |.|:.|..|..                    ||.::||..|
Human   482 PSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFG 546

  Fly   456 LFLGFSVLGFVE----VIYFFTIRIV 477
            .::|.|||..:|    :|.|..|.|:
Human   547 FWMGGSVLCLIEFGEIIIDFVWITII 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	112/601 (19%)
SCNN1B	XP_016879014.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820