DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk10 and ppk21

DIOPT Version :9

Sequence 1:	NP_001033894.1	Gene:	ppk10 / 3885617	FlyBaseID:	FBgn0065110	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	123/551 - (22%)
Similarity:	204/551 - (37%)	Gaps:	131/551 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KNSKYRNGLKIVINYFVLYFNNCCIHGFRYLTDSML--ILFEKFLWLILLIASIYFCIIVCLSSI 66
            |||:.......::.|...|.....:||.|||.|..:  .|..:.:||::|:.:....|:|.:...
  Fly    33 KNSRLGKLWHFMLPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLN 97

  Fly    67 DRYYTKSTHIGIERNYI-FWNTTLPSVTVCPVDRLN----ITYFADYCRNNGIKGPQRDILWDFL 126
            :.|.|......|:...: .:....||:.:||.:|||    .|...|:.....:...|:|:...|.
  Fly    98 ELYQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGANVSAAQKDLFVKFF 162

  Fly   127 ENLANSTYINFQNIPQNEQIDQIIEDIGLKPEHYTELIYNLTYDRTYEPNFNERIRCMDGAMFIH 191
            ....:         |...:::::....|.|.  .|:.::.|.:....|.....:.||.|   ..|
  Fly   163 TAAGD---------PHLSRLNEMSNFFGNKT--LTDELHMLDHLDLREVYKFIQFRCQD---LFH 213

  Fly   192 --------------VRQVLTEWGLCYLGNSKLTEEYSSRYFIFGKYPEYNKYEYENIRLP-YQVG 241
                          :....||.|||::.|::::.  :||       .:..:.:|..:|.| |..|
  Fly   214 TCRWRGNPVNCCEVIEYQFTEAGLCFVFNTEISP--ASR-------QKAREDKYYPLRTPHYGEG 269

  Fly   242 S----FFQKDTQYALLGFKGPAIIA------------FAHSAFEVMKVDSNSDYAYDGILYDLST 290
            |    |.:.:..:...|.:|..::.            ..|.|...:.:                |
  Fly   270 SGLDLFLRLNRSFIRPGKRGINVMIKQPQQWSDVVRHVPHEAHTRISI----------------T 318

  Fly   291 EEITAEDNLEQDTTVAMRRCRF------PHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFY 349
            ...|..|...:..|..:|||.|      ||..|...|.::..| |:..|.......:|||.|..:
  Fly   319 PRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGN-CRSRCHQEHVLNLCKCSPSIF 382

  Fly   350 PNRIANPKPVCDYKTLRSCFPHHASFFLKLY------------EENGKHENP----AICYCEQNC 398
                   .|:.|.....:|   .||.|..||            ||:...:||    .||.|..:|
  Fly   383 -------FPISDKDNFTAC---KASDFKCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSC 437

  Fly   399 ----HDSVVTMKSM-----NPMSGAKQLLGGIGSAVSVKTW---PQSRLRRQVIFSLTDLLVSIG 451
                .|.|.|..::     :..:|..:|     .......|   .|:.:|    |:..:||.|.|
  Fly   438 SQLVFDRVFTTTTLDNNETDTEAGTMRL-----DIFYQSGWFIQYQTNMR----FTFVELLASFG 493

  Fly   452 GTAGLFLGFSVLGFVEVIYFFTIRIVFQILG 482
            |..|||||.|:|...|:.|:|:|.:...|.|
  Fly   494 GIIGLFLGASLLSAFELAYYFSIGLYLYIHG 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	114/520 (22%)
ppk21	NP_651704.2	ASC	51..513	CDD:279230	114/520 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920