Protein Alignment ppk10 and asic2

DIOPT Version :10

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 536
• Identity: 103/536 - (19%)
• Similarity: 177/536 - (33%)
• Gaps: 201/536 - (37%)

  Fly    28 IHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLS-----SIDR---YYTKSTHIGIERNYIF 84
            :||.|::......|..:..|:|.      ||  .||.     |.:|   :....||   .|.:..
Zfish    73 LHGLRHICSPSNSLSRRAFWMIA------FC--TCLGLLLSWSSNRLLHWLAFPTH---TRVHTE 126

  Fly    85 WNTTL--PSVTVC---PVDRLNIT----YFADY-----CRNNGIKGPQRDILWD----FLENLAN 131
            |...|  |:||:|   ||...::|    |||.:     ..|...:....|:|.|    :...|::
Zfish   127 WAKELAFPTVTICNNNPVRLYHLTKSDLYFAGHWLGLLLANRTARPLVLDLLQDDRRGWFSKLSD 191

  Fly   132 -----------STYINFQNIPQNEQIDQIIEDIGLKPEHYTELIYNLTYDRTYEP----NFNERI 181
                       .|.:.|.     :::...:||:.|..::            ..||    ||:
Zfish   192 FRLFLPPRRFEGTSLEFM-----DRLGHQLEDMLLACKY------------RGEPCGAHNFS--- 236

  Fly   182 RCMDGAMFIHVRQVLTEWGLCYLGNSKLTEEYSSRYFIFGKYPEYNKYEYENIRLPYQVGS---- 242
                        .|.|.:|.||:.|:  .||        ||          .:|...:.|:
Zfish   237 ------------TVFTRYGKCYMFNA--AEE--------GK----------TLRTTMKGGTGNGL 269

  Fly   243 ----FFQKDTQYALLGFKGPAIIAFAHSAFEV---MKVDSNSD--YAYD---GILYDLSTEEITA 295
                ..|:|....:.|       ....:|||.   :::.|.::  :.::   |:.....|...|.
Zfish   270 EIMLDIQQDEYLPVWG-------ETEETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQTFVATQ 327

  Fly   296 EDNLE-------QDTTVAMRRCRFPHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPNRI 353
            |..|.       :..:.|:       :|.|  |..|:.:.|:.||......:.|.|...:.|
Zfish   328 EQRLTYLPPPWGECVSRAL-------DSGL--FQVYSVSACRIECETRYIVENCNCRMVYMP--- 380

  Fly   354 ANPKPVCDYKTLRSCFPHHASFFLKLYEENGKHENPAI----------CYCEQNC----HDSVVT 404
             ...|.|..:..:.|                  ..||:          |.|...|    ::..::
Zfish   381 -GDSPYCTPEQYKDC------------------AEPALAALSAVEGTNCICRSPCNMTRYNKELS 426

  Fly   405 MKSMNPMSGAKQL-----------------LGGIGSAVSVKTWPQSRLRRQVIFSLTDLLVSIGG 452
            |..:...:.|:.|                 |.....|::.:|..|.:     .:.:..||..|||
Zfish   427 MVKIPSKTSARYLEKKFNRSEKYITDNILVLDVFFEALNYETIEQKK-----AYEVAGLLGDIGG 486

  Fly   453 TAGLFLGFSVLGFVEV 468
            ..|||:|.|:|..:|:
Zfish   487 QMGLFIGASILTLLEL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:459966	103/536 (19%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	103/536 (19%)