DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk10 and ppk6

DIOPT Version :9

Sequence 1:	NP_001033894.1	Gene:	ppk10 / 3885617	FlyBaseID:	FBgn0065110	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	110/532 - (20%)
Similarity:	183/532 - (34%)	Gaps:	122/532 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KNSKYRNGLK----------IVINYFVLYFNNCCIHGFRYLTDSMLILFEKFLW----LILLIAS 54
            ||||.....|          .::..|..|.....:.|...:..:......:|:|    |.||:.|
  Fly    13 KNSKGDGSRKRGKDPSLIRTAILATFWEYTERTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLS 77

  Fly    55 IYFCIIVCLSSIDRYYTKSTHIGIERNYIFWNTTLPSVTVCPVDRLNITYFADYCRNNGIKGPQR 119
            ||..:::.|    ::|:......|..:....:...|.||:|....:|......|.:.  :|.|:.
  Fly    78 IYLTLLLWL----KFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVDRYVKT--LKIPKE 136

  Fly   120 DILWDFLENLANSTYINFQNIPQNEQIDQIIEDIGLKPEHYTELIYNLTYDRTYEPNFNERIRCM 184
               :|..|.:|...::       |...||..|..|......|:.:..|.....:|........|.
  Fly   137 ---YDMAEVIAGFDFL-------NAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAAMAVSPGCF 191

  Fly   185 DGAMFIHVRQVLTEWGLCYLGNSKLTEEYSSRYFIF-------GKYPEYNKYEYENIR-LPYQVG 241
            |     :|::       |:.|:::.....|..|..|       |....:| |...|.. :|:. .
  Fly   192 D-----YVKR-------CFWGHTEFQCNQSHEYLSFIPTTAYLGPCCSFN-YNPRNASFVPFS-A 242

  Fly   242 SFFQKDTQYALLGFKG------PAIIAFAHSAFEVMKVDSNSDYAYDGILYDLSTEEITA--EDN 298
            :.|..|.....:|.:|      ..:|...|...         ||..:.    .::..|||  |..
  Fly   243 NIFGMDGGLTFVGAEGSERNLNTGLIVLVHHPM---------DYVTEA----AASVTITAQSESF 294

  Fly   299 LEQDTTV------------AMRRCRFPHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPN 351
            :|...||            ..|.|....:..|::   |.:..|...|:.....|.|.|.|:..|
  Fly   295 VEVSPTVQSSSVEVLELSERKRDCLISGDLQLSN---YRQAACLLACQTEAIVKKCGCHPYLLP- 355

  Fly   352 RIANPKPVCDYKTLRSCFPHHASFFLKLYEENGKHENPAICYCEQ---NCHDSVVTMKSMNPMSG 413
            .:.|....|:   |...|.:.|::           :|.....|:|   ||:|  ||..:::..:.
  Fly   356 IVGNKFKECN---LNDTFCYSANY-----------DNFKSVRCDQCLPNCYD--VTYSTLSYKTD 404

  Fly   414 AKQ------------LLGGIGSAVSVKTWPQ--SRLRRQVIFSLTDLLVSIGGTAGLFLGFSVLG 464
            ..|            ||......:.|....|  ..:|:..:.|...||..:||...|.||.|::.
  Fly   405 LNQHKYSVSRFYSPELLNNDSFVLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGLSMIS 469

  Fly   465 FVEVIYFFTIRI 476
            .||..|:.|.|:
  Fly   470 VVEFFYYCTYRL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	101/497 (20%)
ppk6	NP_611461.3	ASC	85..476	CDD:279230	91/453 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920