DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk10 and ppk18

DIOPT Version :9

Sequence 1:	NP_001033894.1	Gene:	ppk10 / 3885617	FlyBaseID:	FBgn0065110	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_609308.3	Gene:	ppk18 / 34295	FlyBaseID:	FBgn0265001	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	561	Identity:	116/561 - (20%)
Similarity:	191/561 - (34%)	Gaps:	178/561 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YFNNCCIHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSSIDRYYTKSTHIGIERNYI-FW 85
            |.|.  :|.|.|.|.   :.:.|.:||..|.|.:.:..||....|..|..:.|.|.:..:.: ..
  Fly    21 YING--LHPFLYHTP---VRYAKAIWLAFLTAIMIYTHIVIADLILEYLVQPTEIHMAPDLVHVA 80

  Fly    86 NTTLPSVTVCPVDRLNITYFADYCR-------NNGIKGPQRDILWDFLENLAN------STYINF 137
            |:..|:|.||..:::|......|..       |:.::....|     |:::||      ..|:|
  Fly    81 NSPFPAVGVCTSNKINGRLLRSYAEKLFHHQGNSSLQAVALD-----LDDMANRLLVLAQFYLN- 139

  Fly   138 QNIPQNEQIDQIIEDIGLKPEH----YTELIYNLTYDRTYEPNFNERIRCMDGAMFIHVRQVLTE 198
                            .|:.:|    .|||      ||.:    ...:...:||.: .||.:|.:
  Fly   140 ----------------PLESDHERWNATEL------DRLH----RLLVAYHNGAGY-SVRDILRD 177

  Fly   199 WGLCYLGNSKLTEEYSSRYFIFGKYPEYNKYEYENIRLPYQVGSFFQK----DTQYALLGFKGPA 259
            .       |....:...|..:||              ||......|.|    .....:..::.|:
  Fly   178 L-------SPGCGDLVIRGIVFG--------------LPVNASQLFLKRPTSSNVCCIFNYRRPS 221

  Fly   260 IIAF----AHSAFEVMKV-----DSNSDY-AYDGILYDLSTEEIT---------------AEDNL 299
            ...|    |....|:..|     :|||.. :...:|.|...|:||               .||..
  Fly   222 YSQFLTKRAEEDSEMRAVPMVVFESNSILNSVQFVLQDTPKEDITNTFHSNSAFQLIIFPQEDYA 286

  Fly   300 E-QDTTVA-------------------------------MRRCRFPHES-NLTHFPFYTRNICQQ 331
            . |.||:.                               :|||.:|.|. .|.:..:|:.:.|..
  Fly   287 TIQSTTLGEVLVDHYSIVEIPIQPMFFSSGDGVRGVPPHIRRCYYPEEGMRLLNQSYYSLDECLL 351

  Fly   332 ECRINLAYKICKCI--PHFYPNRIANPKPVCDYKTL---------RSCFPHHASFFLKLYEENGK 385
            .||:......|.|:  |      :.......||..|         :|.:..::.|   .|.:| |
  Fly   352 VCRMKSMIDHCGCVSPP------LTGSSMDLDYCMLPDLPCLMRWKSIWYGYSDF---AYLQN-K 406

  Fly   386 HENPAICYCEQ---NCHD---SVVT-----MKSMNPMSGAKQLLGGIGS---AVSVKTWPQSRL- 435
            .||.....||.   .|:.   |:.|     .::.|.......||.|:.:   ...:|.:.:.|.
  Fly   407 EENLVQRQCEHCLPTCNGVSMSITTNVAPLRRTYNSSGYFTGLLKGLTNERPLAIIKLFFKLRFA 471

  Fly   436 ---RRQVIFSLTDLLVSIGGTAGLFLGFSVLGFVEVIYFFT 473
               :.|::.|...||...||...|..|||::.::|::|:.|
  Fly   472 QATKSQMVSSWVVLLNRFGGILSLMYGFSIVSYIEILYYLT 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	114/557 (20%)
ppk18	NP_609308.3	ASC	16..510	CDD:279230	114/557 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020