Protein Alignment ppk10 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 119/606 - (19%)
• Similarity: 193/606 - (31%)
• Gaps: 220/606 - (36%)

  Fly    19 FVLYFNNCCIHGFRYLTDSMLILFEKFLWLILLIASI-----YFCIIVCLSSIDRY--YTKSTHI 76
            |..:.||..|||...|..|.....:...|.:|.:.:.     .|.::     .:.|  |..|.:|
  Rat    85 FQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALL-----FEEYLSYPVSLNI 144

  Fly    77 GIERNYIFWNTTLPSVTVCPVDRLNIT----------------------YFADYCRNNGI-KGPQ 118
            .:..:.:    ..|:||||.::....|                      |.:.|.|..|. :...
  Rat   145 NLNSDKL----VFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSS 205

  Fly   119 RDILWDF---LENL-------------ANSTYINFQNIPQNEQIDQIIEDIG--LKPEHYTELIY 165
            ||:|..|   |:.|             :.|:.:.    ..|.|:|:....||  |..::.::..|
  Rat   206 RDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVR----DNNPQVDRKDWKIGFQLCNQNKSDCFY 266

  Fly   166 NLTYDRTYEPNFNERIRCMDGAMFIHVRQVLTEWGLCYLGNSKLTEEYSSRYFI----FGKYPEY 226
                 :||.... :.:|......:|::...|::       .|...||.:...||    |.:.| .
  Rat   267 -----QTYSSGV-DAVREWYRFHYINILSRLSD-------TSPALEEEALGNFIFTCRFNQAP-C 317

  Fly   227 NKYEYENIRLPYQVGSFFQKDTQYALLGFKGPAIIAFAHSAFEVMKVDSNSDYAYDGILYDLSTE 291
            |:..|.....|.....:...|...:.|..                   |:.....:|:...|.||
  Rat   318 NQANYSKFHHPMYGNCYTFNDKNNSNLWM-------------------SSMPGVNNGLSLTLRTE 363

  Fly   292 E----------------ITAED----------NLEQ--DTTVAMRR------------CRFPHES 316
            :                :..:|          ||..  :|:::||:            |    ..
  Rat   364 QNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKEALDSLGGNYGDC----TE 424

  Fly   317 NLTHFPF-------YTRNICQQECRINLAYKICKCIPHFYPNRIANPKPV--CDYKTLRS---CF 369
            |.:..|.       ||:.:|...|......|.|.|...|||    .||.|  |||:...|   |:
  Rat   425 NGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYP----KPKGVEFCDYRKQSSWGYCY 485

  Fly   370 PHHASFFLKLYEENGKHENPAI-CY--CEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSVKT-- 429
                      |:..|.....:: |:  |.:.|  ||:..|          |..|.....|||:
  Rat   486 ----------YKLQGAFSLDSLGCFSKCRKPC--SVINYK----------LSAGYSRWPSVKSQD 528

  Fly   430 WPQSRLRRQ----------------VIF--------------SLTDLLVSIGGTAGLFLGFSVLG 464
            |....|..|                :.|              ::..||.::|....|:.|.|||.
  Rat   529 WIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLS 593

  Fly   465 FVEVIYFFTIRIVFQILGYTL 485
            .||:     ..::|.:|..||
  Rat   594 VVEM-----AELIFDLLVITL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	114/587 (19%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	119/606 (20%)
		deg-1	88..600	CDD:273309	114/592 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820